Publication: Advanced Medical Therapies in the Management of Non-Scarring Alopecia: Areata and Androgenic Alopecia
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Date
2020-11-09
Authors
Martinez-Lopez, Antonio
Montero-Vilchez, Trinidad
Sierra-Sánchez, Álvaro
Molina-Leyva, Alejandro
Arias-Santiago, Salvador
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MDPI
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Abstract
Alopecia is a challenging condition for both physicians and patients. Several topical, intralesional, oral, and surgical treatments have been developed in recent decades, but some of those therapies only provide partial improvement. Advanced medical therapies are medical products based on genes, cells, and/or tissue engineering products that have properties in regenerating, repairing, or replacing human tissue. In recent years, numerous applications have been described for advanced medical therapies. With this background, those therapies may have a role in the treatment of various types of alopecia such as alopecia areata and androgenic alopecia. The aim of this review is to provide dermatologists an overview of the different advanced medical therapies that have been applied in the treatment of alopecia, by reviewing clinical and basic research studies as well as ongoing clinical trials.
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MeSH Terms
Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia
Medical Subject Headings::Organisms::Eukaryota::Animals
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering
Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia::Alopecia Areata
Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Dermatology
Medical Subject Headings::Anatomy::Integumentary System::Skin
Medical Subject Headings::Anatomy::Tissues::Epithelium::Epidermis::Hair Follicle
Medical Subject Headings::Organisms::Eukaryota::Animals
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Culture Techniques::Cell Engineering::Tissue Engineering
Medical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Hair Diseases::Hypotrichosis::Alopecia::Alopecia Areata
Medical Subject Headings::Disciplines and Occupations::Health Occupations::Medicine::Dermatology
Medical Subject Headings::Anatomy::Integumentary System::Skin
Medical Subject Headings::Anatomy::Tissues::Epithelium::Epidermis::Hair Follicle
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Keywords
Androgenic alopecia, Alopecia areata, Mesenchymal stem cells, Advanced medical therapies, Tissue engineering, Gene therapy, Alopecia, Células madre mesenquimatosas, Ingeniería de tejidos, Terapia genética
Citation
Martinez-Lopez A, Montero-Vilchez T, Sierra-Sánchez Á, Molina-Leyva A, Arias-Santiago S. Advanced Medical Therapies in the Management of Non-Scarring Alopecia: Areata and Androgenic Alopecia. Int J Mol Sci. 2020 Nov 9;21(21):8390