Publication: Control of tumor angiogenesis and metastasis through modulation of cell redox state.
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2020-02-05
Authors
Serrano, José J
Delgado, Belén
Medina, Miguel Ángel
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Abstract
Redox reactions pervade all biology. The control of cellular redox state is essential for bioenergetics and for the proper functioning of many biological functions. This review traces a timeline of findings regarding the connections between redox and cancer. There is ample evidence of the involvement of cellular redox state on the different hallmarks of cancer. Evidence of the control of tumor angiogenesis and metastasis through modulation of cell redox state is reviewed and highlighted.
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MeSH Terms
Disease Progression
Humans
Neoplasms
Neovascularization, Pathologic
Oxidation-Reduction
Signal Transduction
Humans
Neoplasms
Neovascularization, Pathologic
Oxidation-Reduction
Signal Transduction
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Keywords
Metastasis, Redox metabolism, Redox signaling, Tumor angiogenesis