Publication: Epidemiology of uterine myomas and clinical practice in Spain: An observational study.
No Thumbnail Available
Identifiers
Date
2018-05-21
Authors
Monleón, Javier
Cañete, María Luisa
Caballero, Virginia
Del Campo, Manuel
Doménech, Alejandro
Losada, Miguel Ángel
Calaf, Joaquim
EME Study Group
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Characterization of the clinical features of symptomatic uterine myomas in Spanish women visiting the gynaecologist, including impact on quality of life and possible risk factors, description of main therapeutic approaches, and evaluation of symptom and quality of life progression 6 months after inclusion in the study. This was an observational, epidemiological, non-interventional, multicentre study performed between June 2015 and March 2016. Data were collected at baseline and follow-up visits 6 months apart from women with a diagnosis of uterine myomas and visiting a participating gynaecologist in outpatient units of private clinics or public hospitals in Spain. Data consisted of a gynaecological clinical inspection, an interview with open questions to the patients, and self-administered generic questionnaires. The main outcome measures were socio-demographic data, clinical history, myoma clinical features, symptomatology, data on surgical choices, patient satisfaction, and risk factors associated to myomas. Data were collected from 569 patients (1,022 myomas) at 56 hospitals and private gynaecological offices in Spain. Most patients (85%) presented between 1 and 3 myomas, predominantly intramural and subserosal. Most common symptoms reported heavy menstrual bleeding and pelvic pain, and the mean (±SD) symptom severity score in the UFS-QoL questionnaire (range 0-100) was 50.89 ± 20.85. Up to 60.5% of patients had an indication of surgery (55.8% myomectomies, 40.4% hysterectomies) to treat their uterine myomas and 39.5% followed other therapies, mainly pharmacological. After six months of treatment, all patients had experienced significant reduction in symptoms and improvement of quality of life. The most frequent symptoms reported by women diagnosed with uterine myomas were heavy menstrual bleeding, pelvic or abdominal pain and dysmenorrhea; QoL was impaired reflecting high symptom distress. We found that surgery was the main therapeutic approach to manage uterine myomas in Spain. Both surgical and non-surgical treatments achieve relevant improvements in symptom severity and quality of life.
Description
MeSH Terms
Adult
Female
Humans
Leiomyoma
Menorrhagia
Middle Aged
Patient Satisfaction
Prevalence
Quality of Life
Risk Factors
Spain
Surveys and Questionnaires
Uterine Neoplasms
Female
Humans
Leiomyoma
Menorrhagia
Middle Aged
Patient Satisfaction
Prevalence
Quality of Life
Risk Factors
Spain
Surveys and Questionnaires
Uterine Neoplasms
DeCS Terms
CIE Terms
Keywords
Abnormal uterine bleeding, Hysterectomy, Myomectomy, Uterine myomas