Publication: Cognitive impairment in patients with fibromyalgia syndrome as assessed by the mini-mental state examination.
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Identifiers
Date
2009-12-21
Authors
Rodríguez Andreu, José
Ibáñez Bosch, Rosario
Portero Vázquez, Amparo
Masramon, Xavier
Rejas, Javier
Gálvez, Rafael
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
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Abstract
This study evaluated the frequency of cognitive impairment in patients with Fibromyalgia syndrome (FMS) using the Mini Mental State Examination (MMSE).
METHODS
We analyzed baseline data from all 46 patients with FMS and 92 age- and sex-matched controls per diagnosis of neuropathic (NeP) or mixed pain (MP) selected from a larger prospective study.
RESULTS
FMS had a slight but statistically significant lower score in the adjusted MMSE score (26.9; 95% CI 26.7-27.1) than either NeP (27.3; 95% CI 27.2-27.4) or MP (27.3; 27.2-27.5). The percentage of patients with congnitive impairment (adjusted MMSE <or= 26) was numerically higher in FMS (15%; 95% CI 6.3-29) compared with NeP (5%; 95% CI 1.8-12.2) or MP (5%; 95% CI 1.8-12.2) and higher than in the same age stratum of the general population (0.05%).
CONCLUSIONS
Compared with the population reference value, patients with FMS showed high frequency of cognitive impairment.
Description
Journal Article; Research Support, Non-U.S. Gov't;
MeSH Terms
Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Emotions::Anxiety
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Delirium, Dementia, Amnestic, Cognitive Disorders::Cognition Disorders
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Comorbidity
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Decision Support Techniques::Data Interpretation, Statistical
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Disability Evaluation
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Diseases::Musculoskeletal Diseases::Muscular Diseases::Fibromyalgia
Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography::Health Status
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Neurological::Neurologic Examination::Pain Measurement
Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography::Sex Distribution
Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography::Age Distribution
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Delirium, Dementia, Amnestic, Cognitive Disorders::Cognition Disorders
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies
Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Epidemiologic Factors::Comorbidity
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Decision Support Techniques::Data Interpretation, Statistical
Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Mood Disorders::Depressive Disorder
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Disability Evaluation
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Diseases::Musculoskeletal Diseases::Muscular Diseases::Fibromyalgia
Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography::Health Status
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged
Medical Subject Headings::Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Neurological::Neurologic Examination::Pain Measurement
Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography::Sex Distribution
Medical Subject Headings::Disciplines and Occupations::Social Sciences::Demography::Age Distribution
DeCS Terms
CIE Terms
Keywords
General-population, Pain, Depression, Prevalence, Spain, Fibromyalgia syndrome, Adjustment Disorders, Trastornos de Adaptación, Dolor, Prevalencia, España, Fibromialgia
Citation
Rodríguez-Andreu J, Ibáñez-Bosch R, Portero-Vázquez A, Masramon X, Rejas J, Gálvez R. Cognitive impairment in patients with fibromyalgia syndrome as assessed by the mini-mental state examination. BMC Musculoskelet Disord; 10:162