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Common Variable Immunodeficiency: Epidemiology, Pathogenesis, Clinical Manifestations, Diagnosis, Classification, and Management.

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dc.contributor.authorYazdani, R
dc.contributor.authorHabibi, S
dc.contributor.authorSharifi, L
dc.contributor.authorAzizi, G
dc.contributor.authorAbolhassani, H
dc.contributor.authorOlbrich, P
dc.contributor.authorAghamohammadi, A
dc.date.accessioned2023-01-25T10:30:37Z
dc.date.available2023-01-25T10:30:37Z
dc.date.issued2019-02-11
dc.description.abstractCommon variable immunodeficiency (CVID) is a heterogeneous disorder characterized by hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is the most frequent symptomatic antibody deficiency, with a wide variety of infectious and noninfectious complications. Numerous studies have demonstrated that immunological and genetic defects are involved in the pathogenesis of CVID. However, in most cases, the genetic background of the disease remains unidentified. This review aims to discuss various aspects of CVID, including epidemiology, pathogenesis, symptoms, diagnosis, classification, and management.
dc.description.versionSi
dc.identifier.citationYazdani R, Habibi S, Sharifi L, Azizi G, Abolhassani H, Olbrich P, et al. Common Variable Immunodeficiency: Epidemiology, Pathogenesis, Clinical Manifestations, Diagnosis, Classification, and Management. J Investig Allergol Clin Immunol. 2020;30(1):14-34.
dc.identifier.doi10.18176/jiaci.0388
dc.identifier.issn1018-9068
dc.identifier.pmid30741636
dc.identifier.unpaywallURLhttp://www.jiaci.org/revistas/vol30issue1_2.pdf
dc.identifier.urihttp://hdl.handle.net/10668/13543
dc.issue.number1
dc.journal.titleJournal of investigational allergology & clinical immunology
dc.journal.titleabbreviationJ Investig Allergol Clin Immunol
dc.language.isoen
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.organizationHospital Universitario Virgen del Rocío
dc.page.number14-34
dc.provenanceRealizada la curación de contenido 03/04/2025
dc.publisherEsmon Publicidad
dc.pubmedtypeJournal Article
dc.pubmedtypeReview
dc.relation.publisherversionhttp://www.jiaci.org/summary/vol30-issue1-num1940
dc.rights.accessRightsRestricted Access
dc.subjectClassifications
dc.subjectCommon variable immunodeficiency
dc.subjectDiagnosis
dc.subjectEpidemiology
dc.subjectManagement
dc.subjectPathogenesis
dc.subjectSymptoms
dc.subject.decsEnfermedad
dc.subject.decsAgammaglobulinemia
dc.subject.decsInmunodeficiencia variable común
dc.subject.decsClasificación
dc.subject.decsRevisión
dc.subject.decsDiagnóstico
dc.subject.decsAntecedentes genéticos
dc.subject.decsInfecciones bacterianas
dc.subject.decsEpidemiología
dc.subject.meshAgammaglobulinemia
dc.subject.meshAnimals
dc.subject.meshCommon Variable Immunodeficiency
dc.subject.meshGene-Environment Interaction
dc.subject.meshHematopoietic Stem Cell Transplantation
dc.subject.meshHumans
dc.subject.meshImmunoglobulins, Intravenous
dc.subject.meshPhenotype
dc.titleCommon Variable Immunodeficiency: Epidemiology, Pathogenesis, Clinical Manifestations, Diagnosis, Classification, and Management.
dc.typeReview
dc.type.hasVersionVoR
dc.volume.number30
dspace.entity.typePublication

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