Publication: Hospitalizaciones infantiles asociadas a infección por virus de la gripe en 6 ciudades de España (2014-2016).
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Identifiers
Date
2018-07-25
Authors
Aristegui-Fernandez, Javier
Gonzalez-Perez-Yarza, Eduardo
Mellado-Peña, Maria Jose
Rodrigo-Gonzalo-de-Liria, Carlos
Hernandez-Sampelayo, Teresa
Garcia-Garcia, Juan Jose
Ruiz-Contreras, Jesus
Moreno-Perez, David
Garrote-Llanos, Elisa
Ramos-Amador, Jose Tomas
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
La información existente sobre el impacto de la gripe en la población infantil española es escasa. El presente trabajo pretende aumentar este conocimiento estudiando aspectos clave como la incidencia de hospitalización, clínica, comorbilidades y el estado vacunal en los niños hospitalizados. Se trató de un estudio retrospectivo, observacional, por revisión de historias clínicas, en menores de 15 años hospitalizados por gripe adquirida en la comunidad, confirmada microbiológicamente durante 2 temporadas gripales (2014-2015 y 2015-2016). El estudio se realizó en 10 hospitales de 6 ciudades, que atienden aproximadamente al 12% de la población infantil española. Fueron hospitalizados 907 niños con diagnóstico principal de gripe (447 < 2 años), con una tasa media anual de incidencia de hospitalización de 0,51 casos/1.000 niños (IC del 95% 0,48-0,55). El 45% presentó enfermedades subyacentes consideradas factores de riesgo para gripe grave, y la mayor parte de ellos (74%) no habían sido vacunados. El porcentaje con enfermedades subyacentes aumentó con la edad, desde el 26% en menores de 6 meses al 74% en mayores de 10 años. El 10% de los casos (n = 92) precisaron cuidados intensivos pediátricos por fallo respiratorio agudo. La gripe es causa importante de hospitalización en la población infantil española. Los menores de 6 meses de edad y los niños con enfermedades subyacentes constituyen una parte mayoritaria (> 50%) de los casos. Una gran parte de las formas graves de gripe en población infantil podrían ser evitadas si se cumplieran las indicaciones actuales de vacunación.
There are only a limited number of studies on the impact of influenza in the Spanish child population. The present work intends to increase this knowledge by studying some key aspects, such as the incidence of hospital admissions, clinic variables, comorbidities, and the vaccination status in the hospitalised children. A retrospective, observational study was conducted by reviewing the medical records of children under 15 years and hospitalised due to community acquired influenza confirmed microbiologically, during 2́flu seasons (2014-2015 and 2015-2016). The study was carried out in 10 hospitals of 6cities, which represent approximately 12% of the Spanish child population. A total of 907 children were admitted to hospital with main diagnosis of influenza infection (447 10 years. Admission to the PICU was required in 10% (92) of the cases, mainly due to acute respiratory failure. Influenza continues to be an important cause of hospitalisation in the Spanish child population. Children 50%) of the cases. Many of the severe forms of childhood influenza that occur today could be avoided if current vaccination guidelines were met.
There are only a limited number of studies on the impact of influenza in the Spanish child population. The present work intends to increase this knowledge by studying some key aspects, such as the incidence of hospital admissions, clinic variables, comorbidities, and the vaccination status in the hospitalised children. A retrospective, observational study was conducted by reviewing the medical records of children under 15 years and hospitalised due to community acquired influenza confirmed microbiologically, during 2́flu seasons (2014-2015 and 2015-2016). The study was carried out in 10 hospitals of 6cities, which represent approximately 12% of the Spanish child population. A total of 907 children were admitted to hospital with main diagnosis of influenza infection (447 10 years. Admission to the PICU was required in 10% (92) of the cases, mainly due to acute respiratory failure. Influenza continues to be an important cause of hospitalisation in the Spanish child population. Children 50%) of the cases. Many of the severe forms of childhood influenza that occur today could be avoided if current vaccination guidelines were met.
Description
MeSH Terms
Adolescent
Child
Child, Preschool
Female
Hospitalization
Humans
Infant
Infant, Newborn
Influenza A virus
Influenza B virus
Influenza Vaccines
Influenza, Human
Male
Retrospective Studies
Spain
Urban Health
Vaccination
Child
Child, Preschool
Female
Hospitalization
Humans
Infant
Infant, Newborn
Influenza A virus
Influenza B virus
Influenza Vaccines
Influenza, Human
Male
Retrospective Studies
Spain
Urban Health
Vaccination
DeCS Terms
Niño
Gripe humana
Población
Vacunación
Incidencia
Insuficiencia respiratoria
Características de la residencia
Gripe humana
Población
Vacunación
Incidencia
Insuficiencia respiratoria
Características de la residencia
CIE Terms
Keywords
Children, Hospital admissions, Hospitalizaciones, Influenza virus, Niños, Virus de la gripe
Citation
Arístegui Fernández J, González Pérez-Yarza E, Mellado Peña MJ, Rodrigo Gonzalo de Liria C, Hernández Sampelayo T, García García JJ, et al. Hospitalizaciones infantiles asociadas a infección por virus de la gripe en 6 ciudades de España (2014-2016) [Child hospital admissions associated with influenza virus infection in 6 Spanish cities (2014-2016)]. An Pediatr (Engl Ed). 2019 Feb;90(2):86-93. Spanish