Publication:
In vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L. leaves

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Date

2020-11

Authors

Rey-Blanes, Cristina
Pérez-Portero, Yalina
Morris-Quevedo, Humberto J.
Casas, Virginia
Abdala, Roberto
Quesada, Ana R.
Martínez-Poveda, Beatriz
Medina, Miguel Ángel

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Elsevier Masson SAS
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Abstract

The traditional ethnobotanic and pharmacologic use of Spondias mombin L. samples includes a wide range of applications. In the present study, new antiangiogenic and antitumor effects of two types of extracts from Spondias mombin L. leaves have been demonstrated by using a number of in vitro assays in both endothelial and human cancer and non cancer cells.

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Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents::Angiogenesis Inhibitors
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agents::Antineoplastic Agents, Phytogenic
Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Cycle
Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Tumor Cells, Cultured::Cell Line, Tumor
Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement
Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Survival
Medical Subject Headings::Anatomy::Cells::Epithelial Cells::Endothelial Cells
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Chemicals and Drugs::Pharmaceutical Preparations::Plant Extracts
Medical Subject Headings::Anatomy::Plant Structures::Plant Components, Aerial::Plant Leaves
Medical Subject Headings::Organisms::Eukaryota::Plants::Viridiplantae::Streptophyta::Embryophyta::Angiosperms::Anacardiaceae

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Keywords

Spondias mombin, Angiogenesis, Antiangiogenic effects, Antitumor effects, Inhibidores de la angiogénesis, Anacardiaceae, Línea celular tumoral, Hojas de la planta

Citation

Rey-Blanes C, Pérez-Portero Y, Morris-Quevedo HJ, Casas V, Abdala R, Quesada AR, et al. In vitro evaluation of the antitumoral and antiangiogenic effects of extracts from Spondias mombin L. leaves. Biomed Pharmacother. 2020 Nov;131:110716.