Publication:
Does the Food Ingredient Pectin Provide a Risk for Patients Allergic to Non-Specific Lipid-Transfer Proteins?

dc.contributor.authorSteigerwald, Hanna
dc.contributor.authorBlanco-Perez, Frank
dc.contributor.authorAlbrecht, Melanie
dc.contributor.authorBender, Caroline
dc.contributor.authorWangorsch, Andrea
dc.contributor.authorEndreß, Hans-Ulrich
dc.contributor.authorBunzel, Mirko
dc.contributor.authorMayorga, Cristobalina
dc.contributor.authorTorres, Maria Jose
dc.contributor.authorScheurer, Stephan
dc.contributor.authorVieths, Stefan
dc.contributor.funderGerman Federal Ministry for Education and Research (BMBF)
dc.contributor.funderAndalusian Regional Ministry of Health
dc.date.accessioned2023-05-03T13:53:34Z
dc.date.available2023-05-03T13:53:34Z
dc.date.issued2021-12-21
dc.description.abstractPectin, a dietary fiber, is a polysaccharide that is widely used in food industry as a gelling agent. In addition, prebiotic and beneficial immunomodulatory effects of pectin have been demonstrated, leading to increased importance as food supplement. However, as cases of anaphylactic reactions after consumption of pectin-supplemented foods have been reported, the present study aims to evaluate the allergy risk of pectin. This is of particular importance since most of the pectin used in the food industry is extracted from citrus or apple pomace. Both contain several allergens such as non-specific lipid transfer proteins (nsLTPs), known to induce severe allergic reactions, which could impair the use of pectins in nsLTP allergic patients. Therefore, the present study for the first time was performed to analyze residual nsLTP content in two commercial pectins using different detection methods. Results showed the analytical sensitivity was diminished by the pectin structure. Finally, spiking of pectin with allergenic peach nsLTP Pru p 3 led to the conclusion that the potential residual allergen content in both pectins is below the threshold to induce anaphylactic reactions in nsLTP-allergic patients. This data suggests that consumption of the investigated commercial pectin products provides no risk for inducing severe reactions in nsLTP-allergic patients.
dc.description.versionSi
dc.identifier.citationSteigerwald H, Blanco-Perez F, Albrecht M, Bender C, Wangorsch A, Endreß HU, et al. Does the Food Ingredient Pectin Provide a Risk for Patients Allergic to Non-Specific Lipid-Transfer Proteins? Foods. 2021 Dec 21;11(1):13
dc.identifier.doi10.3390/foods11010013
dc.identifier.issn2304-8158
dc.identifier.pmcPMC8750200
dc.identifier.pmid35010137
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8750200/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2304-8158/11/1/13/pdf?version=1640152640
dc.identifier.urihttp://hdl.handle.net/10668/20973
dc.issue.number1
dc.journal.titleFoods (Basel, Switzerland)
dc.journal.titleabbreviationFoods
dc.language.isoen
dc.organizationHospital Universitario Regional de Málaga
dc.organizationInstituto de Investigación Biomédica de Málaga-IBIMA
dc.page.number16
dc.provenanceRealizada la curación de contenido 25/03/2025
dc.publisherMDPI
dc.publisherPE-0039-2018
dc.publisherRC-004-2021
dc.pubmedtypeJournal Article
dc.relation.projectIDBMBF-ERA 01EA1901
dc.relation.projectIDAC18/00031
dc.relation.publisherversionhttps://www.mdpi.com/resolver?pii=foods11010013
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectPru p 3
dc.subjectFood allergy
dc.subjectNon-specific lipid transfer protein
dc.subjectnsLTP
dc.subjectPectin
dc.subject.decsPectinas
dc.subject.decsHipersensibilidad
dc.subject.decsIndustria de Alimentos
dc.subject.decsAnafilaxia
dc.subject.decsAlérgenos
dc.subject.decsAlimentos Fortificados
dc.subject.meshAnaphylaxis
dc.subject.meshPectins
dc.subject.meshFood, Fortified
dc.subject.meshPrebiotics
dc.subject.meshCitrus
dc.subject.meshDietary Supplements
dc.subject.meshFood Industry
dc.titleDoes the Food Ingredient Pectin Provide a Risk for Patients Allergic to Non-Specific Lipid-Transfer Proteins?
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number11
dspace.entity.typePublication

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