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A selective culture medium for screening linezolid-resistant gram-positive bacteria.

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dc.contributor.authorNordmann, Patrice
dc.contributor.authorRodriguez-Villodres, Angel
dc.contributor.authorPoirel, Laurent
dc.contributor.funderSwiss National Science Foundation
dc.date.accessioned2023-01-25T13:32:39Z
dc.date.available2023-01-25T13:32:39Z
dc.date.issued2019-03-21
dc.description.abstractThe SuperLinezolid medium was developed for screening resistance to linezolid (LZD) in Gram-positive bacteria (Staphylococcus spp., Enterococcus spp.). It was evaluated using LZD-susceptible (n = 20) and LZD-resistant (n = 17) Gram-positive isolates. The sensitivity was found to be 82% at 24 h (3 out of 17 isolates being missed), and reached 100% at 48 h. At 48 h, a single LZD-susceptible isolate grew (specificity 95%). By testing stools spiked with LZD-resistant Gram-positive strains, an excellent performance of the medium was observed, with a lowest detection limit ranging from 101 to 102 CFU/ml. Overall, this medium is accurate for detection of LZD-resistant Gram-positive isolates after 24 h of culture.
dc.description.versionSi
dc.identifier.citationNordmann P, Rodríguez-Villodres A, Poirel L. A selective culture medium for screening linezolid-resistant gram-positive bacteria. Diagn Microbiol Infect Dis. 2019 Sep;95(1):1-4.
dc.identifier.doi10.1016/j.diagmicrobio.2019.03.006
dc.identifier.essn1879-0070
dc.identifier.pmid30981556
dc.identifier.unpaywallURLhttp://doc.rero.ch/record/327450/files/nor_scm.pdf
dc.identifier.urihttp://hdl.handle.net/10668/13824
dc.issue.number1
dc.journal.titleDiagnostic microbiology and infectious disease
dc.journal.titleabbreviationDiagn Microbiol Infect Dis
dc.language.isoen
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.organizationHospital Universitario Virgen del Rocío
dc.organizationHospital Universitario Virgen del Rocío
dc.page.number4
dc.provenanceRealizada la curación de contenido 07/03/2025
dc.publisherElsevier Inc.
dc.pubmedtypeJournal Article
dc.relation.projectIDFNS-407240_177382
dc.relation.publisherversionhttps://linkinghub.elsevier.com/retrieve/pii/S0732-8893(19)30096-3
dc.rights.accessRights Restricted Access
dc.subjectAntibiotic
dc.subjectEnterococci
dc.subjectLinezolid
dc.subjectScreening
dc.subjectStaphylococci
dc.subject.decsSensibilidad y especificidad
dc.subject.decsEsguinces y distensiones
dc.subject.decsLímite de detección
dc.subject.decsEnterococcus
dc.subject.decsLinezolid
dc.subject.decsDiagnóstico
dc.subject.decsStaphylococcus
dc.subject.decsTamizaje masivo
dc.subject.decsCultura
dc.subject.decsBacterias Grampositivas
dc.subject.meshAnti-Bacterial Agents
dc.subject.meshBacteriological Techniques
dc.subject.meshCulture Media
dc.subject.meshDrug Resistance, Bacterial
dc.subject.meshEnterococcus
dc.subject.meshFeces
dc.subject.meshGram-Positive Bacteria
dc.subject.meshHumans
dc.subject.meshLinezolid
dc.subject.meshMicrobial Sensitivity Tests
dc.subject.meshSensitivity and Specificity
dc.subject.meshStaphylococcus
dc.titleA selective culture medium for screening linezolid-resistant gram-positive bacteria.
dc.typeresearch article
dc.type.hasVersionSMUR
dc.volume.number95
dspace.entity.typePublication

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