Publication: Reference values for TSH may be inadequate to define hypothyroidism in persons with morbid obesity: Di@bet.es study.
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2017-03-09
Authors
Valdés, Sergio
Maldonado-Araque, Cristina
Lago-Sampedro, Ana
Lillo-Muñoz, Juan Antonio
Garcia-Fuentes, Eduardo
Perez-Valero, Vidal
Gutiérrez-Repiso, Carolina
Garcia-Escobar, Eva
Goday, Albert
Urrutia, Inés
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Abstract
To analyze the reference range of thyroid-stimulating hormone (TSH) in different BMI categories and its impact on the classification of hypothyroidism. The study included 3,928 individuals free of thyroid disease (without previous thyroid disease, no interfering medications, TSH The reference range (p2.5-97.5) for TSH was estimated as 0.6 to 4.8 µUI/mL in the underweight category (BMI Persons with morbid obesity might be inappropriately classified if the standard ranges of normality of TSH for the normal-weight population are applied to them.
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MeSH Terms
Adolescent
Adult
Aged
Aged, 80 and over
Autoantibodies
Cross-Sectional Studies
Female
Humans
Hypothyroidism
Male
Middle Aged
Obesity, Morbid
Observer Variation
Overweight
Prevalence
Reference Values
Spain
Thinness
Thyroid Function Tests
Thyrotropin
Thyroxine
Triiodothyronine
Young Adult
Adult
Aged
Aged, 80 and over
Autoantibodies
Cross-Sectional Studies
Female
Humans
Hypothyroidism
Male
Middle Aged
Obesity, Morbid
Observer Variation
Overweight
Prevalence
Reference Values
Spain
Thinness
Thyroid Function Tests
Thyrotropin
Thyroxine
Triiodothyronine
Young Adult