Publication: [Overweight and obesity at risk factors for hypertensive states of pregnancy: a retrospective cohort study].
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Date
2018-08-02
Authors
Fernández Alba, Juan Jesús
Mesa Páez, Cristina
Vilar Sánchez, Ángel
Soto Pazos, Estefanía
González Macías, María Del Carmen
Serrano Negro, Estefanía
Paublete Herrera, María Del Carmen
Moreno Corral, Luis Javier
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Abstract
obesity has been associated with an increased risk of preeclampsia and gestational hypertension. to determine if overweight and/or maternal obesity at the beginning of the pregnancy are associated with an increased risk of suffering from some hypertensive state of pregnancy in a population of southern Spain. retrospective cohort study. We studied 4,711 cases where the IMC had been registered at the beginning of pregnancy. Two study groups were included: overweight/obesity at the beginning of the gestation. pregnant women with normal BMI at the beginning of gestation. Global risk of hypertensive disorders of pregnancy (HDP) and the risk of gestational hypertension, preeclampsia, chronic hypertension and preeclampsia superimposed on chronic hypertension were evaluated. maternal overweight was associated with an increased risk of HDP (OR 2.04, 95% CI: 1.43-2.91) and an increased risk of gestational hypertension (OR 1.68, 95% CI: 1.03-2.72) and chronic HT (OR: 3.70, 95% CI: 1.67-8.18). Maternal obesity was associated with an increase in some HDP (OR 3.54, 95% CI: 2.65-4.73), gestational hypertension (OR 2.94, 95% CI: 2-4.33), chronic HT (OR 8.31, 95% CI: 4.23-16.42) and preeclampsia (OR 2.08, 95% CI: 1.12-3.87) In the multivariate analysis (adjusted for parity and maternal age), overweight was associated with an increased risk of gestational hypertension (OR: 1.74, 95% CI: 1.06-2.85), chronic HT (OR 3.76, 95% CI: 1.69-8.35) and preeclampsia (OR 2.12, 95% CI: 1.005-4.48); obesity also increased the risk of gestational hypertension (OR 2.40, 95% CI: 1.39-4.13), chronic hypertension (OR 17.96, 95% CI: 8.78-36.76) and preeclampsia (OR 3, 69; 95% CI: 1.64-8.27). in conclusion, a significant and independent association was found between maternal overweight/obesity and HDP. The risk is significantly higher as the BMI increases (from overweight to obesity grade 3).
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MeSH Terms
Adult
Body Mass Index
Female
Humans
Hypertension, Pregnancy-Induced
Obesity
Overweight
Pre-Eclampsia
Pregnancy
Pregnancy Complications, Cardiovascular
Retrospective Studies
Risk Factors
Spain
Body Mass Index
Female
Humans
Hypertension, Pregnancy-Induced
Obesity
Overweight
Pre-Eclampsia
Pregnancy
Pregnancy Complications, Cardiovascular
Retrospective Studies
Risk Factors
Spain