Publication:
COVID-19-related Mortality During the First 60 Days After Kidney Transplantation.

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Date

2020-06-12

Authors

Pascual, Julio
Melilli, Edoardo
Jimenez-Martin, Carlos
Gonzalez-Monte, Esther
Zarraga, Sofía
Gutierrez-Dalmau, Alex
Lopez-Jimenez, Veronica
Juega, Javier
Muñoz-Cepeda, Miguel
Lorenzo, Inmaculada

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Elsevier
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Abstract

The COVID-19 pandemic prompted the decision to suspend most organ transplantation programs in affected countries, especially in Europe [1]. A recent large population-based report revealed that the cohort at highest risk of in-hospital death due to COVID-19 was the organ transplant population, with a hazard ratio of 4.27 [2]. Published experiences have been restricted to long-term stable kidney transplant (KT) recipients. Despite initial low mortality reported from China [3], further case series have shown mortality rates of up to 75% [4]. The decision to suspend KT programs has been arbitrary, as no reports of COVID-19 in the most vulnerable population, that is, patients with a very recent KT and profound immunosuppression, are available.

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MeSH Terms

Adult
Aged
Betacoronavirus
COVID-19
Coronavirus Infections
Female
Host-Pathogen Interactions
Humans
Immunocompromised Host
Immunosuppressive Agents
Kidney Transplantation
Male
Middle Aged
Opportunistic Infections
Pandemics
Pneumonia, Viral
Registries
Risk Assessment
Risk Factors
SARS-CoV-2
Spain
Time Factors
Treatment Outcome

DeCS Terms

Informe de Investigación
Trasplantes
Poblaciones Vulnerables
Trasplante de Órganos
Terapia de Inmunosupresión

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Keywords

Transplants, Decision Making, Mortality, Immunosuppression Therapy, Organ Transplantation

Citation

Pascual J, Melilli E, Jiménez-Martín C, González-Monte E, Zárraga S, Gutiérrez-Dalmau A, et al. COVID-19-related Mortality During the First 60 Days After Kidney Transplantation. Eur Urol. 2020 Oct;78(4):641-643