Publication:
Standardization procedure for flow cytometry data harmonization in prospective multicenter studies.

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dc.contributor.authorLe Lann, Lucas
dc.contributor.authorJouve, Pierre-Emmanuel
dc.contributor.authorAlarcón-Riquelme, Marta
dc.contributor.authorJamin, Christophe
dc.contributor.authorPers, Jacques-Olivier
dc.contributor.authorPRECISESADS Flow Cytometry Study Group
dc.contributor.authorPRECISESADS Clinical Consortium
dc.date.accessioned2023-02-09T09:36:53Z
dc.date.available2023-02-09T09:36:53Z
dc.date.issued2020-07-14
dc.description.abstractOne of the most challenging objective for clinical cytometry in prospective multicenter immunomonitoring trials is to compare frequencies, absolute numbers of leukocyte populations and further the mean fluorescence intensities of cell markers, especially when the data are generated from different instruments. Here, we describe an innovative standardization workflow to compare all data to carry out any large-scale, prospective multicentric flow cytometry analysis whatever the duration, the number or type of instruments required for the realization of such projects.
dc.identifier.doi10.1038/s41598-020-68468-3
dc.identifier.essn2045-2322
dc.identifier.pmcPMC7360585
dc.identifier.pmid32665668
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360585/pdf
dc.identifier.unpaywallURLhttps://www.nature.com/articles/s41598-020-68468-3.pdf
dc.identifier.urihttp://hdl.handle.net/10668/15937
dc.issue.number1
dc.journal.titleScientific reports
dc.journal.titleabbreviationSci Rep
dc.language.isoen
dc.organizationCentro Pfizer-Universidad de Granada-Junta de Andalucía de Genómica e Investigación Oncológica-GENYO
dc.page.number11567
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subject.meshBiomarkers
dc.subject.meshFlow Cytometry
dc.subject.meshHumans
dc.subject.meshLeukocytes
dc.subject.meshProspective Studies
dc.subject.meshReference Standards
dc.titleStandardization procedure for flow cytometry data harmonization in prospective multicenter studies.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number10
dspace.entity.typePublication

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