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[Recommendations of the Spanish Society of Paediatric Cardiology and Congenital Heart Disease as regards the use of drugs in attention deficit hyperactivity disorder in children and adolescents with a known heart disease, as well as in the general paediatric population: Position statement by the Spanish Paediatric Association].

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2019-10-30

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Pérez-Lescure Picarzo, Javier
Centeno Malfaz, Fernando
Collell Hernández, Rosa
Crespo Marcos, David
Fernández Soria, Teresa
Manso García, Begoña
Rojo Sombrero, Henar
Sabaté Rotés, Anna
Sarquella-Brugada, Georgia

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Abstract

Approved drugs for attention deficit hyperactivity disorder (ADHD) in Spain are methylphenidate, lisdexamphetamine, atomoxetine and guanfacine. Due to adverse cardiovascular effects, mainly increased blood pressure and heart rate, its use in patients with known or undiagnosed heart disease may be controversial. To obtain a consensus document from the Spanish Society of Paediatric Cardiology and Congenital Heart Diseases (SECPCC) and experts from other Agencies and Societies as a guide for the paediatric cardiologist and physicians who treat children and adolescents with ADHD. An analysis was performed on the bibliography and Clinical Practice Guidelines, technical data sheets approved by the Spanish Agency of Medicines and Health Devices, and the Spanish Ministry of Health Guidelines. A Working Group was formed, with a Coordinator, as well as members of the Clinical Cardiology Working Group and Arrhythmia Group of the SECPCC. This Group produced a preliminary document that was reviewed by a group of external experts and a group of internal experts of the SECPCC with a consensus being reached on the final document. The recommendations of the SECPCC and the group of experts are presented on cardiovascular evaluation prior to treatment in children and adolescents with no known cardiovascular disease and with known cardiovascular disease. The recommendations of the SECPCC and the group of experts are also presented on the use of medications for ADHD in children and adolescents with cardiological symptoms with no evidence of heart disease, congenital heart disease, cardiomyopathy, Marfan syndrome and other aortic diseases, hypertension, and arrhythmias.

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MeSH Terms

Adolescent
Attention Deficit Disorder with Hyperactivity
Child
Drug-Related Side Effects and Adverse Reactions
Heart Defects, Congenital
Humans
Spain

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Keywords

Acquired heart disease, Atomoxetina, Atomoxetine, Cardiopatías adquiridas, Cardiopatías congénitas, Cardiovascular side effects, Congenital heart defects, Efectos secundarios cardiovasculares, Guanfacina, Guanfacine, Lisdexamphetamine, Lisdexanfetamina, Methylphenidate, Metilfenidato, Muerte súbita, Sudden death

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