Publication:
Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health.

dc.contributor.authorAmpatzoglou, Antonis
dc.contributor.authorGruszecka-Kosowska, Agnieszka
dc.contributor.authorTorres-Sanchez, Alfonso
dc.contributor.authorLopez-Moreno, Ana
dc.contributor.authorCerk, Klara
dc.contributor.authorOrtiz, Pilar
dc.contributor.authorMonteoliva-Sanchez, Mercedes
dc.contributor.authorAguilera, Margarita
dc.contributor.funderEU-FORA Program (Cycle 2020/2021 and 2021/2022)
dc.contributor.funderFEDER-Microbiota Infrastructure: IE19_198 UGR, OBEMIRISK EFSA-Partnering
dc.contributor.funderEuropa Investigación EIN2019-103082.
dc.date.accessioned2023-05-03T13:41:50Z
dc.date.available2023-05-03T13:41:50Z
dc.date.issued2022-03-031
dc.description.abstractThree areas of relevance to the gut microbiome in the context of One Health were explored; the incorporation of the microbiome in food safety risk assessment of xenobiotics; the identification and application of beneficial microbial components to various areas under One Health, and; specifically, in the context of antimicrobial resistance. Although challenging, focusing on the microbiota resilience, function and active components is critical for advancing the incorporation of microbiome data in the risk assessment of xenobiotics. Moreover, the human microbiota may be a promising source of beneficial components, with the potential to metabolize xenobiotics. These may have possible applications in several areas, e.g., in animals or plants for detoxification or in the environment for biodegradation. This approach would be of particular interest for antimicrobials, with the potential to ameliorate antimicrobial resistance development. Finally, the concept of resistance to xenobiotics in the context of the gut microbiome may deserve further investigation.
dc.description.versionSi
dc.identifier.citationAmpatzoglou A, Gruszecka-Kosowska A, Torres-Sánchez A, López-Moreno A, Cerk K, Ortiz P, et al. Incorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health. Front Microbiol. 2022 May 4;13:872583.
dc.identifier.doi10.3389/fmicb.2022.872583
dc.identifier.issn1664-302X
dc.identifier.pmcPMC9116292
dc.identifier.pmid35602014
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9116292/pdf
dc.identifier.unpaywallURLhttps://www.frontiersin.org/articles/10.3389/fmicb.2022.872583/pdf
dc.identifier.urihttp://hdl.handle.net/10668/20623
dc.journal.titleFrontiers in microbiology
dc.journal.titleabbreviationFront Microbiol
dc.language.isoen
dc.organizationInstituto de Investigación Biosanitaria de Granada (ibs.GRANADA)
dc.page.number7
dc.provenanceRealizada la curación de contenido 20/08/2024
dc.publisherFrontiers Research Foundation
dc.pubmedtypeJournal Article
dc.relation.projectIDGP/EFSA/ENCO/2018/03-GA04
dc.relation.publisherversionhttps://doi.org/10.3389/fmicb.2022.872583
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectantimicrobial resistance
dc.subjectgut microbiome
dc.subjectmicrobiota disrupting chemicals
dc.subjectnext-generation probiotics
dc.subjectnext-generation risk assessment
dc.subjectone health
dc.subjectxenobiotics
dc.subject.decsAnimales
dc.subject.decsAntibacterianos
dc.subject.decsAntiinfecciosos
dc.subject.decsFarmacorresistencia bacteriana
dc.subject.decsHumanos
dc.subject.decsMicrobioma gastrointestinal
dc.subject.decsMicrobiota
dc.subject.decsResiliencia psicológica
dc.subject.decsSalud única
dc.subject.decsXenobióticos
dc.subject.meshHumans
dc.subject.meshAnimals
dc.subject.meshGastrointestinal Microbiome
dc.subject.meshAnti-Bacterial Agents
dc.subject.meshXenobiotics
dc.subject.meshOne Health
dc.subject.meshResilience, Psychological
dc.subject.meshDrug Resistance, Bacterial
dc.subject.meshMicrobiota
dc.subject.meshAnti-Infective Agents
dc.titleIncorporating the Gut Microbiome in the Risk Assessment of Xenobiotics and Identifying Beneficial Components for One Health.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number13
dspace.entity.typePublication

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