Publication:
Novel genes and sex differences in COVID-19 severity.

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Date

2022-06-01

Authors

Cruz, Raquel
Diz-de Almeida, Silvia
Lopez de Heredia, Miguel
Quintela, Ines
Ceballos, Francisco C
Pita, Guillermo
Lorenzo-Salazar, Jose M
Gonzalez-Montelongo, Rafaela
Gago-Dominguez, Manuela
Sevilla Porras, Marta

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Oxford University Press
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Abstract

Here, we describe the results of a genome-wide study conducted in 11 939 coronavirus disease 2019 (COVID-19) positive cases with an extensive clinical information that were recruited from 34 hospitals across Spain (SCOURGE consortium). In sex-disaggregated genome-wide association studies for COVID-19 hospitalization, genome-wide significance (P 

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MeSH Terms

Female
Male
Middle Aged
Polymorphism, Single Nucleotide
COVID-19
Genetic Loci
Genetic Predisposition to Disease

DeCS Terms

Femenino
Masculino
Persona de mediana edad
Polimorfismo de nucleótido simple
Predisposición genética a la enfermedad
Sitios genéticos

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Keywords

Humans, Genome-Wide Association Study, Sex Characteristics

Citation

Cruz R, Diz-de Almeida S, López de Heredia M, Quintela I, Ceballos FC, Pita G, et al. Novel genes and sex differences in COVID-19 severity. Hum Mol Genet. 2022 Nov 10;31(22):3789-3806.