Publication:
Incorporating zeolitic-imidazolate framework-8 nanoparticles into kidney scaffolds: a first step towards innovative renal therapies.

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Date

2022-11-01

Authors

Guerrero, Fatima
Pulido, Victoria
Hamad, Said
Aljama, Pedro
Martin-Malo, Alejandro
Carrillo-Carrion, Carolina

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Royal Society of Chemistry
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Abstract

We demonstrate for the first time the potential of zeolitic-imidazolate framework-8 nanoparticles to be incorporated within a renal scaffold while retaining their ability to remove uremic toxins (mainly hydrophobic toxins like p-cresol) under flow conditions. This work may pave the way for the future development of novel adsorbents for dialysis and/or artificial kidneys.

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MeSH Terms

Zeolites
Kidney
Renal dialysis
Kidneys, artificial

DeCS Terms

Riñón
Zeolitas
Diálisis renal
Riñones artificiales

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Keywords

Uremic toxins, 4-cresol, Nanoparticles

Citation

Guerrero F, Pulido V, Hamad S, Aljama P, Martín-Malo A, Carrillo-Carrión C. Incorporating zeolitic-imidazolate framework-8 nanoparticles into kidney scaffolds: a first step towards innovative renal therapies. Nanoscale. 2022 Dec 8;14(47):17543-17549.