Publication: Inclusiones nucleares que orientan a alteraciones moleculares en leucemias agudas: 2 casos con inclusiones cup-like
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Identifiers
Date
2015-10-22
Authors
Kestler Gonzalez, K
Arbelo Granado, E
Rodriguez Fernandez, A
Rojas Noboa, J
Dominguez Velazquez, N
Fernandez Roman, I
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Ferrata Storti Foundation
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Abstract
La clasificación actual de la OMS para Leucemias Mieloides Agudas (LMA) combina hallazgos morfológicos, inmunofenotipicos
y moleculares. La duplicación interna del tándem del gen FLT3 y la mutación en el exón 12 del gen Nucleofosmina NPM1 son alteraciones genéticas conocidas en la LMA y se asocian a blastos con inclusiones
nucleares conocidas como invaginaciones en huella dactilar (IHD), tipo“cup-like” o “fish-mouth”.
Description
MeSH Terms
Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Gene Components::Exons
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Anatomy::Body Regions::Head::Face::Mouth
Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Family::Nuclear Family
Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Reproductive History::Parity
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Reoperation
Medical Subject Headings::Check Tags::Female
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Anatomy::Body Regions::Head::Face::Mouth
Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Family::Nuclear Family
Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Reproductive History::Parity
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Reoperation
DeCS Terms
CIE Terms
Keywords
Exones, Boca, Paridad, Reoperación, Leucocitosis, anemia, plaquetopenia
Citation
Kestler Gonzalez K, Arbelo Granado E, Rodriguez Fernandez A, Rojas Noboa J, Dominguez Velazquez N, Fernandez Roman I. Inclusiones nucleares que orientan a alteraciones moleculares en leucemias agudas: 2 casos con inclusiones cup-like. Haematologica. 2015;vol.100 supplement 4 pag. 237