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[Positive effect of a propolis supplement on lipid profile, glycemia, and hepatic antioxidant status in an experimental animal model].

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2020

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Lisbona-González, Maria Jesus
Reyes-Botella, Candela
Muñoz-Soto, Esther
Vallecillo-Rivas, Marta
Moreno Fernandez, Jorge
Díaz Castro, Javier

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Abstract

Introduction: the use of natural nutritional supplements can be used as a coadjuvant therapy since they have several phytochemicals with potential antioxidant effects that could influence lipid and glycemic metabolism. Objectives: to determine the effect of natural propolis supplementation on lipid metabolism and liver antioxidant activity. Material and methods: 20 male Wistar albino rats (8 weeks) were divided into two groups of 10 animals each. Subsequently, they were fed two different types of diet for 90 days: a standard diet for the control group (diet C) and a standard diet + 2 % propolis (diet P). Hematological and biochemical parameters were assessed. The livers were extracted and washed with saline solution, and the cytosolic fractions were prepared fresh for additional analysis of antioxidant enzymes catalase, superoxide dismutase, glutathione peroxidase, and glutathione reductase. Results: after consuming the diet supplemented with propolis, we found a reduction in glucose (p

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MeSH Terms

Animals
Antioxidants
Blood Glucose
Dietary Supplements
Lipid Metabolism
Liver
Male
Models, Animal
Propolis
Rats
Rats, Wistar

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Keywords

Propóleo. Perfil lipídico. Perfil glucémico. Estrés oxidativo. Transaminasas.

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