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Glycaemic efficacy and safety of linagliptin for the management of non-cardiac surgery patients with type 2 diabetes in a real-world setting: Lina-Surg study.

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Date

2019-05-21

Authors

Pérez-Belmonte, Luis M
Osuna-Sánchez, Julio
Millán-Gómez, Mercedes
López-Carmona, María D
Gómez-Doblas, Juan J
Cobos-Palacios, Lidia
Sanz-Cánovas, Jaime
Barbancho, Miguel A
Lara, José P
Jiménez-Navarro, Manuel

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Abstract

Introduction: The use of dipeptidyl peptidase-4 inhibitors in hospitalized patients is an area of active research. We aimed to compare the efficacy and the safety of the basal-bolus insulin regimen versus linagliptin-basal insulin in non-critically ill non-cardiac surgery patients in a real-world setting. Methods: We enrolled patients with type 2 diabetes hospitalized in non-cardiac surgery departments with admission glycated haemoglobin level 200 mg/dL (p = .199), and treatment failures (p = .395). Total daily insulin and number of daily insulin injections were lower in the linagliptin-basal group (both p 

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MeSH Terms

Aged
Blood Glucose
Diabetes Mellitus, Type 2
Dipeptidyl-Peptidase IV Inhibitors
Drug Therapy, Combination
Female
Glycated Hemoglobin
Hospitalization
Humans
Hypoglycemia
Hypoglycemic Agents
Insulin
Linagliptin
Male
Middle Aged
Safety
Spain
Treatment Failure
Treatment Outcome

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Keywords

Diabetes mellitus, inpatient hyperglycaemia, linagliptin, non-cardiac surgery

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