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Association of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study.

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dc.contributor.authorOrgaz-Molina, Jacinto
dc.contributor.authorMagro-Checa, César
dc.contributor.authorArrabal-Polo, Miguel A
dc.contributor.authorRaya-Álvarez, Enrique
dc.contributor.authorNaranjo, Ramón
dc.contributor.authorBuendía-Eisman, Agustín
dc.contributor.authorArias-Santiago, Salvador
dc.contributor.authoraffiliation[Orgaz-Molina,J; Ramón Naranjo,E; Buendía-Eisman,A; Arias-Santiago,S] Dermatology Department San Cecilio; University Hospital; Granada, Spain. [Magro-Checa,C; Raya-Álvarez,E] Rheumatology Department, San Cecilio; University Hospital [Arrabal-Polo,M A; Raya-Álvarez,E; Buendía-Eisman, A; Arias-Santiago, S;] School of Medicine, University of Granada, Spain. [Arias-Santiago,S] Baza General Hospital, Granada, Spaines
dc.date.accessioned2015-04-07T09:19:57Z
dc.date.available2015-04-07T09:19:57Z
dc.date.issued2014-03
dc.descriptionJournal Article;es
dc.description.abstractVitamin D deficiency is associated with higher cardiovascular risk and metabolic syndrome (MeS) criteria. The main objective of this study was to analyse the association of 25-hydroxyvitamin D (25-OHD) serum levels with MeS (National Cholesterol Education Program-Adult Treatment Panel-III criteria) in 46 Spanish patients with psoriasis, but without arthritis and systemic treatment, and 46 control subjects, matched by sex and age. The patients with psoriasis showed significantly lower level of 25-OHD than controls (30.5 vs. 38.3 ng/ml; p = 0.0001). Patients with MeS had significantly lower serum levels of 25-OHD than those without MeS (24.1 ± 7.5 vs. 32.8 ± 8.9, p = 0.007), and a negative correlation was found between 25-OHD and waist circumference, diastolic blood pressure, fasting glucose, and triglyceridaemia. In the control group no significant correlation between 25-OHD and MeS was found. Al-though the sample was small, our results suggest a potential protective role for 25-OHD in the metabolic profile of patients with psoriasis without arthritis.es
dc.description.versionYeses
dc.identifier.citationOrgaz-Molina J, Magro-Checa C, Arrabal-Polo MA, Raya-Álvarez E, Naranjo R, Buendía-Eisman A, et al. Association of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study. Acta Derm. Venereol.. 2014; 94(2):142-5es
dc.identifier.doi10.2340/00015555-1642
dc.identifier.essn1651-2057
dc.identifier.issn0001-5555
dc.identifier.pmid23995104
dc.identifier.urihttp://hdl.handle.net/10668/1861
dc.journal.titleActa dermato-venereologica
dc.language.isoen
dc.publisherSociety for Publication of Acta Dermato-Venereologicaes
dc.relation.publisherversionhttp://www.medicaljournals.se/acta/content/?volume=94&issue=2es
dc.rights.accessRightsopen access
dc.subjectPsoriasises
dc.subjectVitamin Des
dc.subjectMetabolic syndromees
dc.subjectCardiovascular riskes
dc.subjectPsoriasises
dc.subjectVitamina Des
dc.subjectEnfermedades metabólicases
dc.subjectEnfermedades cardiovasculareses
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Mass Indexes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studieses
dc.subject.meshMedical Subject Headings::Check Tags::Femalees
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models, Theoretical::Models, Statistical::Logistic Modelses
dc.subject.meshMedical Subject Headings::Check Tags::Malees
dc.subject.meshMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Metabolic Syndrome Xes
dc.subject.meshMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Agedes
dc.subject.meshMedical Subject Headings::Diseases::Skin and Connective Tissue Diseases::Skin Diseases::Skin Diseases, Papulosquamous::Psoriasises
dc.subject.meshMedical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electromagnetic Radiation::Light::Sunlightes
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Vitamin D-Binding Proteines
dc.subject.meshMedical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Malnutrition::Deficiency Diseases::Avitaminosis::Vitamin D Deficiencyes
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Vital Signs::Blood Pressurees
dc.titleAssociation of 25-hydroxyvitamin D with metabolic syndrome in patients with psoriasis: a case-control study.es
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication

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