Publication: Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain.
dc.contributor.author | Leiva-Gea, Isabel | |
dc.contributor.author | Fernández, Cristina Antúnez | |
dc.contributor.author | Cardona-Hernandez, Roque | |
dc.contributor.author | Lozano, Marta Ferrer | |
dc.contributor.author | Bahíllo-Curieses, Pilar | |
dc.contributor.author | Arroyo-Díez, Javier | |
dc.contributor.author | León, María Clemente | |
dc.contributor.author | Martín-Frías, Maria | |
dc.contributor.author | Barreiro, Santiago Conde | |
dc.contributor.author | Delgado, Andrés Mingorance | |
dc.contributor.author | Sánchez, Jacobo Pérez | |
dc.contributor.author | Diabetes Group of the Spanish Pediatric Endocrinology Society (SEEP) | |
dc.date.accessioned | 2023-05-03T14:08:52Z | |
dc.date.available | 2023-05-03T14:08:52Z | |
dc.date.issued | 2022-07-26 | |
dc.description.abstract | Objective: To assess the impact of the COVID-19 pandemic and lockdown measures on the presenting characteristics (age at diagnosis, severity, monthly distribution) of newly diagnosed type 1 diabetes in Spanish children. Research DesignandMethods: An ambispective observational multicenter study was conducted in nine Spanish tertiary-level hospitals between January 2015 and March 2021. Inclusion criteria: new cases of type 1 diabetes in children (0-14 years) recording age, sex, date of diagnosis, presence of diabetic ketoacidosis (DKA) at onset, and severity of DKA. Data were compared before and during the pandemic. Results: We registered 1444 new cases of type 1 diabetes in children: 1085 in the pre-pandemic period (2015-2019) and 359 during the pandemic (2020-March 2021). There was a significant increase in the group aged ≤4 years in the pandemic period (chi-squared = 10.986, df 2, p = 0.0041). In 2020-2021, cases of DKA increased significantly by 12% (95% CI: 7.2-20.4%), with a higher percentage of moderate and severe DKA, although this increase was not significant. In 2020, there was a sharp decrease in the number of cases in March, with a progressive increase from May through November, higher than in the same months of the period 2015-2019, highlighting the increase in the number of cases in June, September, and November. The first three months of 2021 showed a different trend to that observed both in the years 2015-2019 and in 2020, with a marked increase in the number of cases. Conclusions: A change in monthly distribution was described, with an increase in DKA at onset of type 1 diabetes. No differences were found in severity, although there were differences in the age distribution, with an increase in the number of cases in children under 4 years of age. | |
dc.identifier.doi | 10.3390/jcm11154338 | |
dc.identifier.issn | 2077-0383 | |
dc.identifier.pmc | PMC9369057 | |
dc.identifier.pmid | 35893428 | |
dc.identifier.pubmedURL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9369057/pdf | |
dc.identifier.unpaywallURL | https://www.mdpi.com/2077-0383/11/15/4338/pdf?version=1659062306 | |
dc.identifier.uri | http://hdl.handle.net/10668/21326 | |
dc.issue.number | 15 | |
dc.journal.title | Journal of clinical medicine | |
dc.journal.titleabbreviation | J Clin Med | |
dc.language.iso | en | |
dc.organization | Área de Gestión Sanitaria Campo de Gibraltar Oeste | |
dc.organization | Hospital Universitario Regional de Málaga | |
dc.organization | Instituto de Investigación Biomédica de Málaga-IBIMA | |
dc.organization | AGS - Campo de Gibraltar Oeste | |
dc.pubmedtype | Journal Article | |
dc.rights | Attribution 4.0 International | |
dc.rights.accessRights | open access | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject | COVID-19 | |
dc.subject | DKA | |
dc.subject | diabetes onset | |
dc.subject | type 1 diabetes | |
dc.title | Increased Presentation of Diabetic Ketoacidosis and Changes in Age and Month of Type 1 Diabetes at Onset during the COVID-19 Pandemic in Spain. | |
dc.type | research article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 11 | |
dspace.entity.type | Publication |
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