Publication:
Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa.

dc.contributor.authorFonte, Luis
dc.contributor.authorAcosta, Armando
dc.contributor.authorSarmiento, Maria E
dc.contributor.authorNorazmi, Mohd Nor
dc.contributor.authorGinori, Maria
dc.contributor.authorde-Armas, Yaxsier
dc.contributor.authorCalderon, Enrique J
dc.date.accessioned2023-05-03T14:23:33Z
dc.date.available2023-05-03T14:23:33Z
dc.date.issued2022-07-30
dc.description.abstractThere is an increasing attention to the emerging health problem represented by the clinical and functional long-term consequences of SARS-CoV-2 infection, referred to as postacute COVID-19 syndrome. Clinical, radiographic, and autopsy findings have shown that a high rate of fibrosis and restriction of lung function are present in patients who have recovered from COVID-19. Patients with active TB, or those who have recovered from it, have fibrotic scarred lungs and, consequently, some degree of impaired respiratory function. Helminth infections trigger predominantly type 2 immune responses and the release of regulatory and fibrogenic cytokines, such as TGF-β. Here, we analyze the possible consequences of the overlapping of pulmonary fibrosis secondary to COVID-19 and tuberculosis in the setting of sub-Saharan Africa, the region of the world with the highest prevalence of helminth infection.
dc.description.versionSi
dc.identifier.citationFonte L, Acosta A, Sarmiento ME, Norazmi MN, Ginori M, de Armas Y, et al. Overlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa. Trop Med Infect Dis. 2022 Jul 30;7(8):157.
dc.identifier.doi10.3390/tropicalmed7080157
dc.identifier.essn2414-6366
dc.identifier.pmcPMC9416620
dc.identifier.pmid36006249
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9416620/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2414-6366/7/8/157/pdf?version=1659316352
dc.identifier.urihttp://hdl.handle.net/10668/21595
dc.issue.number8
dc.journal.titleTropical medicine and infectious disease
dc.journal.titleabbreviationTrop Med Infect Dis
dc.language.isoen
dc.organizationHospital Universitario Virgen del Rocío
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.page.number8
dc.provenanceRealizada la curación de contenido 24/06/2025.
dc.publisherMDPI AG
dc.pubmedtypeJournal Article
dc.relation.publisherversionhttps://www.mdpi.com/resolver?pii=tropicalmed7080157
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjecthelminth coinfection
dc.subjectpostacute COVID-19 syndrome
dc.subjectpulmonary fibrosis
dc.subjectsub-Saharan Africa
dc.subjecttuberculosis
dc.subject.decsPulmón
dc.subject.decsInfecciones
dc.subject.decsPacientes
dc.subject.decsTuberculosis
dc.subject.decsFibrosis pulmonar
dc.subject.decsInmunidad
dc.subject.decsSíndrome
dc.subject.meshPulmonary fibrosis
dc.subject.meshCytokines
dc.subject.meshCicatrix
dc.subject.meshTuberculosis
dc.subject.meshImmunity
dc.subject.meshHelminths
dc.titleOverlapping of Pulmonary Fibrosis of Postacute COVID-19 Syndrome and Tuberculosis in the Helminth Coinfection Setting in Sub-Saharan Africa.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number7
dspace.entity.typePublication

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