Publication: Cancer Incidence in Heart Transplant Recipients With Previous Neoplasia History.
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2016-02-03
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Delgado, J F
Alonso-Pulpón, L
Mirabet, S
Almenar, L
Villa, F P
González-Vílchez, F
Palomo, J
Blasco, T
Dolores García-Cosio, M
González-Costello, J
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Abstract
Neoplasm history increases morbidity and mortality after solid organ transplantation and has disqualified patients from transplantation. Studies are needed to identify factors to be considered when deciding on the suitability of a patient with previous tumor for heart transplantation. A retrospective epidemiological study was conducted in heart transplant (HT) recipients (Spanish Post-Heart Transplant Tumor Registry) comparing the epidemiological data, immu-nosuppressive treatments and incidence of post-HT tumors between patients with previous malignant noncardiac tumor and with no previous tumor (NPT). The impact of previous tumor (PT) on overall survival (OS) was also assessed. A total of 4561 patients, 77 PT and 4484 NPT, were evaluated. The NPT group had a higher proportion of men than the PT group (p
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MeSH Terms
Aged
Female
Follow-Up Studies
Heart Diseases
Heart Transplantation
Humans
Incidence
Male
Middle Aged
Neoplasms
Postoperative Complications
Prognosis
Retrospective Studies
Risk Factors
Spain
Time Factors
Female
Follow-Up Studies
Heart Diseases
Heart Transplantation
Humans
Incidence
Male
Middle Aged
Neoplasms
Postoperative Complications
Prognosis
Retrospective Studies
Risk Factors
Spain
Time Factors