Publication:
Further Advances in Atrial Fibrillation Research: A Metabolomic Perspective

dc.contributor.authorArbeloa-Gomez, Laura
dc.contributor.authorAlvarez-Vidal, Jaime
dc.contributor.authorIzquierdo-Garcia, Jose Luis
dc.contributor.authoraffiliation[Arbeloa-Gomez, Laura] Univ Pablo Olavide, Dept Biotecnol Sanitaria, Seville 41013, Spain
dc.contributor.authoraffiliation[Alvarez-Vidal, Jaime] Univ Pablo Olavide, Dept Biotecnol Sanitaria, Seville 41013, Spain
dc.contributor.authoraffiliation[Arbeloa-Gomez, Laura] Inst Biomed Seville IBiS, Clin Unit Infect Dis Microbiol & Prevent Med, Seville 41013, Spain
dc.contributor.authoraffiliation[Alvarez-Vidal, Jaime] Biomedal SL, Dept ID, Seville 41900, Spain
dc.contributor.authoraffiliation[Izquierdo-Garcia, Jose Luis] Univ Complutense Madrid, Pharm Sch, Dept Chem Pharmaceut Sci, NMR & Imaging Biomed Grp, Madrid 28040, Spain
dc.contributor.authoraffiliation[Izquierdo-Garcia, Jose Luis] CIBERES, CIBER Enfermedades Resp, Madrid 28029, Spain
dc.contributor.authoraffiliation[Izquierdo-Garcia, Jose Luis] Univ Complutense Madrid, Inst Pluridisciplinar, Madrid 28040, Spain
dc.contributor.funderSpanish Ministry of Science and Innovation
dc.contributor.funderComunidad de Madrid, Madrid, Spain
dc.contributor.funderEuropean Union's Horizon 2020 Research and Innovation Program, under the Marie Sklodowska-Curie grant
dc.date.accessioned2023-05-03T13:47:12Z
dc.date.available2023-05-03T13:47:12Z
dc.date.issued2022-03-21
dc.description.abstractAtrial fibrillation involves an important type of heart arrhythmia caused by a lack of control in the electrical signals that arrive in the heart, produce an irregular auricular contraction, and induce blood clotting, which finally can lead to stroke. Atrial fibrillation presents some specific characteristics, but it has been treated and prevented using conventional methods similar to those applied to other cardiovascular diseases. However, due to the influence of this pathology on the mortality caused by cerebrovascular accidents, further studies on the molecular mechanism of atrial fibrillation are required. Our aim here is provide a compressive review of the use of metabolomics on this condition, from the study of the metabolic profile of plasma to the development of animal models. In summary, most of the reported studies highlighted alterations in the energetic pathways related to the development of the condition.
dc.description.versionSi
dc.identifier.citationArbeloa-Gómez L, Álvarez-Vidal J, Izquierdo-García JL. Further Advances in Atrial Fibrillation Research: A Metabolomic Perspective. Applied Sciences. 2022; 12(6):3201.
dc.identifier.doi10.3390/app12063201
dc.identifier.essn2076-3417
dc.identifier.unpaywallURLhttps://www.mdpi.com/2076-3417/12/6/3201/pdf?version=1647934288
dc.identifier.urihttp://hdl.handle.net/10668/20794
dc.identifier.wosID775833200001
dc.issue.number6
dc.journal.titleApplied sciences-basel
dc.journal.titleabbreviationAppl. sci.-basel
dc.language.isoen
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.provenanceRealizada la curación de contenido 20/05/2025.
dc.publisherMdpi
dc.relation.projectIDB2017/BMD3875
dc.relation.projectID823854
dc.relation.publisherversionhttps://www.mdpi.com/2076-3417/12/6/3201
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectatrial fibrillation
dc.subjectheart arrhythmia
dc.subjectmetabolomics
dc.subjectmetabolic profile
dc.subjectStroke prevention
dc.subjectBile-acids
dc.subjectRisk
dc.subject.decsFibrilación Atrial
dc.subject.decsAccidente cerebrovascular
dc.subject.decsCoagulación sanguínea
dc.subject.decsEnfermedades cardiovasculares
dc.subject.decsArritmias cardíacas
dc.subject.meshAtrial Fibrillation
dc.subject.meshCardiovascular Diseases
dc.subject.meshArrhythmias, Cardiac
dc.subject.meshBlood Coagulation
dc.subject.meshCardiovascular Diseases
dc.titleFurther Advances in Atrial Fibrillation Research: A Metabolomic Perspective
dc.typereview
dc.type.hasVersionVoR
dc.volume.number12
dc.wostypeArticle
dspace.entity.typePublication

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