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Relationship between nutritional treatment compliance and nutritional status improvements in patients with gastrointestinal impairment taking an oral peptide-based supplement.

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2022-05-21

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López-Medina, José A
López-Rodriguez, Cristóbal
Estornell-Gualde, María A
Rey-Fernández, Laura
Gómez-Senent, Silvia
Joaquín-Ortiz, Clara
Fernández-Soto, M Luisa
Hurtado-García, Roberto
Martín-Martín, Margarita
Barrera-Martín, Ana

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Abstract

Compliance in outpatients with gastrointestinal (GI) malabsorption is key in nutritional treatment. The objective of this study was to assess compliance in patients with GI impairment and malnutrition taking a high-calorie, high-protein, peptide-based oral nutritional supplement (ONS-PBD). A prospective, multicenter, observational study was conducted in 19 medical sites in Spain where ONS-PBD were prescribed as standard of care. Patients consumed ONS-PBD daily for 12 wk. Compliance was calculated as the percentage consumed of the prescribed amount of ONS per day. A total of 90 adult patients were included in the study, of whom 64 completed the 12-wk regimine. Mean compliance was 78.8% ± 24.5%. Risk of malnutrition decreased in 56.3% of patients at 12 wk, as measured with the malnutrition universal screening tool. A reduction in abdominal pain was observed and stool consistency improved, with a mean of 54.7% and 27.5%, respectively. Improvements in quality of life and a decrease in percentage of patients with severe functional impairment were observed. These data show that ONS-PBD compliance in malnourished patients with GI symptoms is high, reducing GI symptoms and improving patients' nutritional status.

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Adult
Dietary Supplements
Humans
Malnutrition
Nutritional Status
Patient Compliance
Peptides
Prospective Studies
Quality of Life

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Keywords

Compliance, Enteral formulas, Enteral nutrition, Gastroenterology, Gastrointestinal diseases, Nutrition, Peptide-based formulas

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