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B-cell chronic lymphocytic leukemia with bilateral ear involvement.

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dc.contributor.authorAndamoyo-Castañeda, Alberto
dc.contributor.authorGodoy-Diaz, Daniel Jesus
dc.contributor.authorAyala-Blanca, Maria
dc.date.accessioned2023-05-03T14:33:47Z
dc.date.available2023-05-03T14:33:47Z
dc.date.issued2022-06
dc.description.abstractA 66-year-old woman presented with multiple, painless, plum-colored nodules in both ears for the past year, associated with partial destruction of the auricular cartilage [Figures 1a and b]. The histopathologic examination revealed a monomorphic lymphocyte infiltrate that expressed CD5, CD20, CD23, CD43 and was negative for CD3, CD10, cyclin D1, Bcl2, and Bcl6. The findings were compatible with B-cell chronic lymphocytic leukemia (CLL-B). The myelogram done showed a lymphocyte clone with a similar immunohistochemical profile. Pan-body CT-scan and blood tests were normal. This patient responded well to local radiation therapy (total dose of 16 Gy) with resolution of the nodules.
dc.description.versionSi
dc.identifier.citationCastañeda AA, Godoy Díaz DJ, Blanca MA. B-cell chronic lymphocytic leukemia with bilateral ear involvement. Indian J Dermatol Venereol Leprol. 2022 May-Jun;88(4):562-563
dc.identifier.doi10.25259/IJDVL_605_20
dc.identifier.essn0973-3922
dc.identifier.pmid33871185
dc.identifier.unpaywallURLhttps://doi.org/10.25259/ijdvl_605_20
dc.identifier.urihttp://hdl.handle.net/10668/21798
dc.issue.number4
dc.journal.titleIndian journal of dermatology, venereology and leprology
dc.journal.titleabbreviationIndian J Dermatol Venereol Leprol
dc.language.isoen
dc.organizationHospital Universitario Regional de Málaga
dc.page.number562-563
dc.provenanceRealizada la curación de contenido 12/03/2025
dc.publisherScientific Scholar LLC
dc.pubmedtypeJournal Article
dc.relation.publisherversionhttps://doi.org/10.25259/IJDVL_605_20
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectLymphocytes
dc.subjectRadiotherapy
dc.subjectHematologic Tests
dc.subjectEar Cartilage
dc.subjectPrunus domestica
dc.subject.decsLinfocitos
dc.subject.decsDosificación
dc.subject.decsMujeres
dc.subject.decsOído
dc.subject.decsPruebas hematológicas
dc.subject.decsLeucemia linfocítica crónica de células B
dc.subject.meshHumans
dc.subject.meshLeukemia, Lymphocytic, Chronic, B-Cell
dc.subject.meshCyclin D1
dc.subject.meshLymphocytes
dc.subject.meshHematologic Tests
dc.subject.meshPrunus domestica
dc.titleB-cell chronic lymphocytic leukemia with bilateral ear involvement.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number88
dspace.entity.typePublication

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