Publication:
Good clinical and cost outcomes using dexrazoxane to treat accidental epirubicin extravasation

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dc.contributor.authorAraque Arroyo, Patricia
dc.contributor.authorUbago Perez, Ruth
dc.contributor.authorFernandez Feijoo, Maria Amalia
dc.contributor.authorCalleja Hernandez, Miguel Angel
dc.contributor.authoraffiliation[Araque Arroyo,P; Ubago Perez,R; Fernandez Feijoo,MA; Calleja Hernandez,MA] Department of Pharmacy, Virgen de las Nieves University Hospital, Granada, Spain.es
dc.date.accessioned2012-10-09T12:18:12Z
dc.date.available2012-10-09T12:18:12Z
dc.date.issued2011-02-24
dc.descriptionCase Reports; Journal Article;es
dc.description.abstractA 75-year-old man diagnosed with lower esophageal adenocarcinoma suffered from epirubicin extravasation during the second cycle of neoadjuvant chemotherapy with epirubicin and oxaliplatin. A full recovery was achieved after treatment with dexrazoxane (Cardioxane® ). This is the first time in our hospital that extravasation of an anthracycline has been treated with dexrazoxane. We used Cardioxane® , approved for the prevention of anthracycline-induced cardiotoxicity, while Savene® is indicated for the treatment of anthracycline extravasation. The treatment was effective, and the selection of Cardioxane® (seven-fold cheaper than Savene® ) yielded a cost saving. Consequently, Cardioxane® has been included in our guidelines for anthracycline extravasation.es
dc.description.versionYeses
dc.identifier.citationArroyo PA, Perez RU, Feijoo MA, Hernandez MA. Good clinical and cost outcomes using dexrazoxane to treat accidental epirubicin extravasation. J Can Res Ther 2010;6:573-4es
dc.identifier.doi10.4103/0973-1482.77081
dc.identifier.essn1998-4138
dc.identifier.issn0973-1482
dc.identifier.pmid21358106
dc.identifier.urihttp://hdl.handle.net/10668/554
dc.journal.titleJournal of Cancer Research and Therapeutics
dc.language.isoen
dc.publisherMedknow Publicationses
dc.relation.publisherversionhttp://www.cancerjournal.net/text.asp?2010/6/4/573/77081es
dc.rights.accessRightsopen access
dc.subjectAncianoes
dc.subjectAntineoplásicoses
dc.subjectAnálisis Costo-Beneficioes
dc.subjectEpirrubicinaes
dc.subjectExtravasación de Materiales Terapéuticos y Diagnósticoses
dc.subjectHumanoses
dc.subjectMasculinoes
dc.subjectRazoxanoes
dc.subjectResultado del Tratamientoes
dc.subjectAnthracyclinees
dc.subjectChemotherapyes
dc.subjectcostes
dc.subjectDesraxozanees
dc.subjectextravasationes
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Antineoplastic Agentses
dc.subject.meshMedical Subject Headings::Health Care::Health Care Economics and Organizations::Economics::Costs and Cost Analysis::Cost-Benefit Analysises
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Organic Chemicals::Hydrocarbons::Hydrocarbons, Cyclic::Hydrocarbons, Aromatic::Polycyclic Hydrocarbons, Aromatic::Naphthacenes::Anthracyclines::Daunorubicin::Doxorubicin::Epirubicines
dc.subject.meshMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Extravasation of Diagnostic and Therapeutic Materialses
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses
dc.subject.meshMedical Subject Headings::Check Tags::Malees
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Piperazines::Diketopiperazines::Razoxanees
dc.subject.meshMedical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Prognosis::Treatment Outcomees
dc.subject.meshMedical Subject Headings::Named Groups::Persons::Age Groups::Adult::Agedes
dc.titleGood clinical and cost outcomes using dexrazoxane to treat accidental epirubicin extravasationes
dc.typeresearch article
dc.type.hasVersionVoR
dspace.entity.typePublication

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