Publication: Outcome of radiosurgery treatment with a linear accelerator in patients with trigeminal neuralgia
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Date
2017-04-01
Authors
Cordero Tous, N.
de la Cruz Sabido, J.
Roman Cutillas, A. M.
Saura Rojas, E. J.
Jorques Infante, A. M.
Olivares Granados, G.
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Elsevier espana slu
Abstract
Introduction: An overview of the effectiveness of radiosurgery in patients diagnosed with trigeminal neuralgia with an analysis of potential predictors of good outcome.Methods: All patients treated with linear accelerator radiosurgery between 2004 and 2011 were analysed. A dose of 60 Gy dose was administered 1 to 2 mm from the root entry zone with a maximum isodose of 20% delivered to the brainstem. Clinical results for pain control and any " side effects were analysed at 12 and 36 months (BNI score).Results: The study included 71 patients (mean follow-up 50.5 months). Pain improvement at 12 months was observed in 68.11% of the total (28.98% with BNI score Hi; 39.12% with BNI score III) and at 36 months in 58.21% (23.88% BNI score I-II; 34.32% BNI score III). Average recovery time was 3.69 months and the relapse rate was 44.68%. Patients with typical pain displayed statistically significant differences in improvement rates at 12 and at 36 months (P
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Keywords
Trigeminal neuralgia, Radiosurgery, Linear accelerator, Typical pain, Neurosurgery, Facial numbness, Gamma-knife surgery, Stereotactic radiosurgery, Recurrent, Nerve, Zone