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SARS-CoV-2-reactive antibody detection after SARS-CoV-2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group.

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dc.contributor.authorPiñana, José Luis
dc.contributor.authorLópez-Corral, Lucia
dc.contributor.authorMartino, Rodrigo
dc.contributor.authorMontoro, Juan
dc.contributor.authorVazquez, Lourdes
dc.contributor.authorPérez, Ariadna
dc.contributor.authorMartin-Martin, Gabriel
dc.contributor.authorFacal-Malvar, Ana
dc.contributor.authorFerrer, Elena
dc.contributor.authorPascual, María-Jesús
dc.contributor.authorSanz-Linares, Gabriela
dc.contributor.authorGago, Beatriz
dc.contributor.authorSanchez-Salinas, Andrés
dc.contributor.authorVillalon, Lucia
dc.contributor.authorConesa-Garcia, Venancio
dc.contributor.authorOlave, Maria T
dc.contributor.authorLópez-Jimenez, Javier
dc.contributor.authorMarcos-Corrales, Sara
dc.contributor.authorGarcía-Blázquez, Marta
dc.contributor.authorGarcia-Gutiérrez, Valentín
dc.contributor.authorHernández-Rivas, José Ángel
dc.contributor.authorSaus, Ana
dc.contributor.authorEspigado, Ildefonso
dc.contributor.authorAlonso, Carmen
dc.contributor.authorHernani, Rafael
dc.contributor.authorSolano, Carlos
dc.contributor.authorFerrer-Lores, Blanca
dc.contributor.authorGuerreiro, Manuel
dc.contributor.authorRuiz-García, Montserrat
dc.contributor.authorMuñoz-Bellido, Juan Luis
dc.contributor.authorNavarro, David
dc.contributor.authorCedillo, Angel
dc.contributor.authorSureda, Anna
dc.contributor.authorInfectious Complications Subcommittee of the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group (GETH-TC)
dc.date.accessioned2023-05-03T13:28:53Z
dc.date.available2023-05-03T13:28:53Z
dc.date.issued2021-11-02
dc.description.abstractThis is a multicenter prospective observational study that included a large cohort (n = 397) of allogeneic (allo-HSCT; (n = 311) and autologous (ASCT) hematopoietic stem cell transplant (n = 86) recipients who were monitored for antibody detection within 3-6 weeks after complete severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination from February 1, 2021, to July 20, 2021. Most patients (n = 387, 97.4%) received mRNA-based vaccines. Most of the recipients (93%) were vaccinated more than 1 year after transplant. Detectable SARS-CoV-2-reactive antibodies were observed in 242 (78%) of allo-HSCT and in 73 (85%) of ASCT recipients. Multivariate analysis in allo-HSCT recipients identified lymphopenia
dc.identifier.doi10.1002/ajh.26385
dc.identifier.essn1096-8652
dc.identifier.pmcPMC8646900
dc.identifier.pmid34695229
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8646900/pdf
dc.identifier.unpaywallURLhttps://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ajh.26385
dc.identifier.urihttp://hdl.handle.net/10668/19952
dc.issue.number1
dc.journal.titleAmerican journal of hematology
dc.journal.titleabbreviationAm J Hematol
dc.language.isoen
dc.organizationHospital Universitario Regional de Málaga
dc.page.number30-42
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
dc.pubmedtypeObservational Study
dc.rights.accessRightsopen access
dc.subject.meshAdolescent
dc.subject.meshAdult
dc.subject.meshAged
dc.subject.meshAntibodies, Viral
dc.subject.meshCOVID-19
dc.subject.meshCOVID-19 Vaccines
dc.subject.meshFemale
dc.subject.meshHematopoietic Stem Cell Transplantation
dc.subject.meshHumans
dc.subject.meshImmunocompromised Host
dc.subject.meshMale
dc.subject.meshMiddle Aged
dc.subject.meshProspective Studies
dc.subject.meshSARS-CoV-2
dc.subject.meshSpain
dc.subject.meshYoung Adult
dc.titleSARS-CoV-2-reactive antibody detection after SARS-CoV-2 vaccination in hematopoietic stem cell transplant recipients: Prospective survey from the Spanish Hematopoietic Stem Cell Transplantation and Cell Therapy Group.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number97
dspace.entity.typePublication

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