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Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies

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dc.contributor.authorMelguizo-Rodríguez, Lucía
dc.contributor.authorCostela-Ruiz, Victor J.
dc.contributor.authorManzano-Moreno, Francisco Javier
dc.contributor.authorRuiz, Concepción
dc.contributor.authorIllescas-Montes, Rebeca
dc.contributor.authoraffiliation[Melguizo-Rodríguez,L] Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences (Ceuta), University of Granada, Granada, Spain. [Melguizo-Rodríguez,L; Costela-Ruiz,VJ; Manzano-Moreno,FJ; Ruiz,C; Illescas-Montes,R] Instituto Investigación Biosanitaria, ibs.Granada, Granada, Spain. [Costela-Ruiz,VJ; Ruiz,C; Illescas-Montes,R]Biomedical Group (BIO277), Department of Nursing, Faculty of Health Sciences, University of Granada, Granada, Spain. [Manzano-Moreno,FJ] Biomedical Group (BIO277), Department of Stomatology, School of Dentistry, University of Granada, Granada, Spain. [Ruiz,C] Institute of Neuroscience, University of Granada, Granada, Spain.
dc.date.accessioned2022-06-03T10:43:40Z
dc.date.available2022-06-03T10:43:40Z
dc.date.issued2020-07-21
dc.description.abstractSaliva is a highly versatile biological fluid that is easy to gather in a non-invasive manner-and the results of its analysis complement clinical and histopathological findings in the diagnosis of multiple diseases. The objective of this review was to offer an update on the contribution of salivary biomarkers to the diagnosis and prognosis of diseases of the oral cavity, including oral lichen planus, periodontitis, Sjögren's syndrome, oral leukoplakia, peri-implantitis, and medication-related osteonecrosis of the jaw. Salivary biomarkers such as interleukins, growth factors, enzymes, and other biomolecules have proven useful in the diagnosis and follow-up of these diseases, facilitating the early evaluation of malignization risk and the monitoring of disease progression and response to treatment. However, further studies are required to identify new biomarkers and verify their reported role in the diagnosis and/or prognosis of oral diseases.es_ES
dc.description.versionYeses_ES
dc.identifier.citationMelguizo-Rodríguez L, Costela-Ruiz VJ, Manzano-Moreno FJ, Ruiz C, Illescas-Montes R. Salivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologies. Int J Mol Sci. 2020 Jul 21;21(14):5173es_ES
dc.identifier.doi10.3390/ijms21145173es_ES
dc.identifier.essn1422-0067
dc.identifier.pmcPMC7403990
dc.identifier.pmid32708341es_ES
dc.identifier.urihttp://hdl.handle.net/10668/3673
dc.journal.titleInternational Journal of Molecular Sciences
dc.language.isoen
dc.page.number17 p.
dc.publisherMDPIes_ES
dc.relation.publisherversionhttps://www.mdpi.com/1422-0067/21/14/5173/htmes_ES
dc.rightsAtribución 4.0 Internacional*
dc.rights.accessRightsAcceso abiertoes_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectSalivary biomarkeres_ES
dc.subjectCytokineses_ES
dc.subjectOral pathologyes_ES
dc.subjectDiagnosises_ES
dc.subjectSalivaes_ES
dc.subjectBiomarcadoreses_ES
dc.subjectCitocinases_ES
dc.subjectPatología bucales_ES
dc.subjectDiagnósticoes_ES
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Biological Factors::Biological Markerses_ES
dc.subject.meshMedical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humanses_ES
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteinses_ES
dc.subject.meshMedical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Cytokines::Interleukinses_ES
dc.subject.meshMedical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Mouth Neoplasms::Leukoplakia, Orales_ES
dc.subject.meshMedical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Lichen Planus, Orales_ES
dc.subject.meshMedical Subject Headings::Anatomy::Body Regions::Head::Face::Mouthes_ES
dc.subject.meshMedical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Necrosis::Osteonecrosises_ES
dc.subject.meshMedical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Peri-Implantitises_ES
dc.subject.meshMedical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Periodontal Diseases::Periodontitises_ES
dc.subject.meshMedical Subject Headings::Anatomy::Fluids and Secretions::Bodily Secretions::Salivaes_ES
dc.subject.meshMedical Subject Headings::Diseases::Stomatognathic Diseases::Mouth Diseases::Salivary Gland Diseases::Xerostomia::Sjogren's Syndromees_ES
dc.titleSalivary Biomarkers and Their Application in the Diagnosis and Monitoring of the Most Common Oral Pathologieses_ES
dc.typereview article
dc.type.hasVersionVoR
dspace.entity.typePublication

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