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Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk.

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dc.contributor.authorPapandreou, Christopher
dc.contributor.authorBabio, Nancy
dc.contributor.authorDiaz-Lopez, Andres
dc.contributor.authorMartinez-Gonzalez, Miguel A
dc.contributor.authorBecerra-Tomas, Nerea
dc.contributor.authorCorella, Dolores
dc.contributor.authorSchröder, Helmut
dc.contributor.authorRomaguera, Dora
dc.contributor.authorVioque, Jesus
dc.contributor.authorAlonso-Gomez, Angel M
dc.contributor.authorWärnberg, Julia
dc.contributor.authorMartinez, Alfredo J
dc.contributor.authorSerra-Majem, Lluís
dc.contributor.authorEstruch, Ramon
dc.contributor.authorMuñoz-Garach, Araceli
dc.contributor.authorLapetra, Jose
dc.contributor.authorPinto, Xavier
dc.contributor.authorTur, Josep A
dc.contributor.authorGarcia-Rios, Antonio
dc.contributor.authorBueno-Cavanillas, Aurora
dc.contributor.authorDelgado-Rodriguez, Miguel
dc.contributor.authorMatia-Martin, Pilar
dc.contributor.authorDaimiel, Lidia
dc.contributor.authorM Sanchez, Vicente
dc.contributor.authorVidal, Josep
dc.contributor.authorVazquez, Clotilde
dc.contributor.authorRos, Emilio
dc.contributor.authorRuiz-Canela, Miguel
dc.contributor.authorBullo, Monica
dc.contributor.authorSorli, Jose V
dc.contributor.authorQuifer, Mireia
dc.contributor.authorColom, Antoni
dc.contributor.authorOncina-Canovas, Alejandro
dc.contributor.authorT Sierra, Lucas
dc.contributor.authorBaron-Lopez, Javier
dc.contributor.authorPerez-Farinos, Napoleon
dc.contributor.authorAbete, Itziar
dc.contributor.authorSanchez-Villegas, Almudena
dc.contributor.authorCasas, Rosa
dc.contributor.authorF Garcia, Jose C
dc.contributor.authorSantos-Lozano, Jose M
dc.contributor.authorCorbella, Emili
dc.contributor.authorDel M Bibiloni, Maria
dc.contributor.authorDiez-Espino, Javier
dc.contributor.authorAsensio, Eva M
dc.contributor.authorTorras, Laura
dc.contributor.authorMorey, Marga
dc.contributor.authorCompañ-Gabucio, Laura
dc.contributor.authorS Lete, Itziar
dc.contributor.authorCenoz-Osinaga, Juan C
dc.contributor.authorCastañer, Olga
dc.contributor.authorSalas-Salvado, Jordi
dc.contributor.funderISCIII, through the Fondo de Investigación para la Salud (FIS)
dc.contributor.funderEuropean Research Council
dc.contributor.funderConsejería de Salud de la Junta de Andalucía
dc.contributor.funderServicio Andaluz de Salud
dc.date.accessioned2023-01-25T13:32:28Z
dc.date.available2023-01-25T13:32:28Z
dc.date.issued2019-03-29
dc.description.abstractThe aim of the study was to evaluate sleep duration and sleep variability in relation to serum uric acid (SUA) concentrations and SUA to creatinine ratio. This is a cross-sectional analysis of baseline data from 1842 elderly participants with overweight/obesity and metabolic syndromein the (Prevención con Dieta Mediterránea) PREDIMED-Plus trial. Accelerometry-derived sleep duration and sleep variability were measured. Linear regression models were fitted to examine the aforementioned associations. A 1 hour/night increment in sleep duration was inversely associated with SUA concentrations (β = 0.07, p = 0.047). Further adjustment for leukocytes attenuated this association (p = 0.050). Each 1-hour increment in sleep duration was inversely associated with SUA to creatinine ratio (β = 0.15, p = 0.001). The findings of this study suggest that longer sleep duration is associated with lower SUA concentrations and lower SUA to creatinine ratio.
dc.description.versionSi
dc.identifier.citationPapandreou C, Babio N, Díaz-López A, Martínez-González MÁ, Becerra-Tomas N, Corella D, et al. Sleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk. Nutrients. 2019 Apr 1;11(4):761
dc.identifier.doi10.3390/nu11040761
dc.identifier.essn2072-6643
dc.identifier.pmcPMC6521014
dc.identifier.pmid30939748
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521014/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2072-6643/11/4/761/pdf?version=1554530118
dc.identifier.urihttp://hdl.handle.net/10668/13784
dc.issue.number4
dc.journal.titleNutrients
dc.language.isoen
dc.organizationHospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba-IMIBIC
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationInstituto de Investigación Biomédica de Málaga-IBIMA
dc.organizationSevilla
dc.page.number10
dc.publisherMDPI
dc.pubmedtypeJournal Article
dc.pubmedtypeMulticenter Study
dc.relation.projectIDPI13/00673
dc.relation.projectIDPI13/00492
dc.relation.projectID2013ACUP00194
dc.relation.projectIDPI0458/2013
dc.relation.projectIDPS0358/2016
dc.relation.projectIDB-0003-2017
dc.relation.publisherversionhttps://www.mdpi.com/2072-6643/11/4/761
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectActigraphy
dc.subjectSerum uric acid
dc.subjectSerum uric acid to creatinine ratio
dc.subjectSleep duration
dc.subject.decsBiomarcadores
dc.subject.decsCreatinina
dc.subject.decsEnfermedades cardiovasculares
dc.subject.decsEstudios transversales
dc.subject.decsFactores de riesgo
dc.subject.decsSueño
dc.subject.decsÁcido úrico
dc.subject.meshAged
dc.subject.meshBiomarkers
dc.subject.meshCardiovascular diseases
dc.subject.meshCreatinine
dc.subject.meshCross-sectional studies
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshMediterranean region
dc.subject.meshMiddle aged
dc.subject.meshRisk factors
dc.subject.meshSleep
dc.subject.meshSpain
dc.subject.meshUric acid
dc.titleSleep Duration is Inversely Associated with Serum Uric Acid Concentrations and Uric Acid to Creatinine Ratio in an Elderly Mediterranean Population at High Cardiovascular Risk.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number11
dspace.entity.typePublication

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