Publication: Correction to: Utility of pulmonary ultrasound to identify interstitial lung disease in patients with rheumatoid arthritis.
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Identifiers
Date
2021-02-21
Authors
Mena-Vazquez, Natalia
Jimenez-Nuñez, Francisco Gabriel
Godoy-Navarrete, Francisco Javier
Manrique-Arija, Sara
Aguilar-Hurtado, Maria Carmen
Romero-Barco, Carmen Maria
Ureña-Garnica, Inmaculada
Espildora, F
Padin-Martin, Maria Isabel
Fernandez-Nebro, Antonio
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Springer
Abstract
Objectives To analyze the diagnostic utility of lung ultrasound (US) to detect interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients comparing with high-resolution computed tomography (HRCT) Patients and methods We performed a cross-sectional, observational study in patients with RA-ILD (cases) controlled with a group of RA patients without ILD (controls) paired by sex, age, and time of disease evolution. Patients were assessed using HRCT, PFT, and US. The main variables were B-line number, evaluation of the lung-US score already described, pleural irregularities, and A pattern US lost. ROC curve analysis was performed to establish the cut-off point of the US B-lines number for detecting the presence of significant RA–ILD in relation to HRCT, and logistic regression analysis was performed to identify the intercostal spaces. Results Seventy-one patients were included, 35 (49.2%) with ILD-RA and 36 (50.8%) RA controls. Regarding US score, we found that the detection of 5.5 lines in a reduced score of 8 intercostal spaces had a sensitivity = 62.2%, specificity = 91.3%, PPV = 88.4%, and NPV = 69.5%. In multivariate analysis, the intercostal spaces which showed independent association with
ILD were 3rd right anterior axillary space (OR [IC 95%] 19.0 [1.3–27.5]), 8th right posterior axillary space (OR [IC 95%] 0.04 [0.0–0.6]), 8th right subscapular space (OR [IC 95%] 16.5 [1.8–45.5]), 9th right paravertebral space (OR [IC 95%] 7.11 [1.0–37.1]), and 2nd left clavicular middle space (OR [IC 95%] 21.9 [1.26–37.8]). Conclusions Lung ultrasound could be a useful tool for ILD diagnosis associated with rheumatoid arthritis. A 8-space reduced score showed a similar total predictive capacity than 72-space score.
Description
MeSH Terms
Logistic Models
Lung Diseases, Interstitial
Arthritis, Rheumatoid
Multivariate Analysis
Tomography
Lung Diseases, Interstitial
Arthritis, Rheumatoid
Multivariate Analysis
Tomography
DeCS Terms
Pulmón
Artritis Reumatoide
Sensibilidad y Especificidad
Enfermedades Pulmonares Intersticiales
Análisis Multivariante
Curva ROC
Artritis Reumatoide
Sensibilidad y Especificidad
Enfermedades Pulmonares Intersticiales
Análisis Multivariante
Curva ROC
CIE Terms
Keywords
Lung, Arthritis, Rheumatoid, Sensitivity and Specificity, Lung Diseases, Interstitial, Tomography
Citation
Mena-Vázquez N, Jimenez-Núñez FG, Godoy-Navarrete FJ, Manrique-Arija S, Aguilar-Hurtado MC, Romero-Barco CM, et al. Utility of pulmonary ultrasound to identify interstitial lung disease in patients with rheumatoid arthritis. Clin Rheumatol. 2021 Jun;40(6):2377-2385