Publication: Among CLL patiens with multiple fish abnormatities, 13Q and 11Q deletions entail the commonest combination in contrast to 11Q and 17P deletions, being the combination with worse outcome
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Date
2016-06-09
Authors
González-Gascón Y Marín, I
Hernández, JA
Hernánez-Sanchez, M
Rodriguez-Vicente, AE
Puiggros, A
Collado, R
Luño, E
González, T
Ruiz-Xivillé, N
Ortega, M
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Publisher
Ferrata Storti Foundation
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Abstract
Fluorescence in-situ hybridization (FISH) defines a hierarchy of genetic changes that predicts survival in CLL. However, multiple abnormalities (MA) may also occur and little is known about its distribution and clinical impact. containing clinical and biological data.
Description
MeSH Terms
Medical Subject Headings::Diseases::Congenital, Hereditary, and Neonatal Diseases and Abnormalities::Congenital Abnormalities::Abnormalities, Multiple
Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Chromosome Aberrations
Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electromagnetic Radiation::Light::Luminescence::Fluorescence
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Histocytological Preparation Techniques::Staining and Labeling::In Situ Hybridization::In Situ Hybridization, Fluorescence
Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Mutation::Chromosome Aberrations
Medical Subject Headings::Phenomena and Processes::Physical Phenomena::Magnetic Phenomena::Electromagnetic Phenomena::Electromagnetic Radiation::Light::Luminescence::Fluorescence
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Histocytological Preparation Techniques::Staining and Labeling::In Situ Hybridization::In Situ Hybridization, Fluorescence
DeCS Terms
CIE Terms
Keywords
Anomalías múltiples, Aberraciones cromosómicas, Fluorescencia, Hibridación fluorescente in situ
Citation
González-Gascón Y Marín I, Hernández JA, Hernánez-Sanchez M, Rodriguez-Vicente AR, Puiggros A, Collado R, et al. Among CLL patiens with multiple fish abnormatities, 13Q and 11Q deletions entail the commonest combination in contrast to 11Q and 17P deletions, being the combination with worse outcome. Haematologica. 2016; 101(s1), pag.429