Publication:
Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort.

dc.contributor.authorMartinez-Urbistondo, Diego
dc.contributor.authorSan Cristobal, RodrigoSan
dc.contributor.authorVillares, Paula
dc.contributor.authorMartinez-Gonzalez, Miguel Angel
dc.contributor.authorBabio, Nancy
dc.contributor.authorCorella, Dolores
dc.contributor.authorDel Val, Jose Luis
dc.contributor.authorOrdovas, Jose M
dc.contributor.authorAlonso-Gomez, Angel M
dc.contributor.authorWärnberg, Julia
dc.contributor.authorVioque, Jesus
dc.contributor.authorRomaguera, Dora
dc.contributor.authorLopez-Miranda, Jose
dc.contributor.authorEstruch, Ramon
dc.contributor.authorTinahones, Francisco J
dc.contributor.authorLapetra, Jose
dc.contributor.authorSerra-Majem, J Luis
dc.contributor.authorBueno-Cavanillas, Aurora
dc.contributor.authorTur, Josep A
dc.contributor.authorMarcos, Alba
dc.contributor.authorPinto, Xavier
dc.contributor.authorDelgado-Rodriguez, Miguel
dc.contributor.authorMatia-Martin, Pilar
dc.contributor.authorVidal, Josep
dc.contributor.authorVazquez, Clotilde
dc.contributor.authorRos, Emilio
dc.contributor.authorBullon Vela, Maria Vanessa
dc.contributor.authorPalau, Antoni
dc.contributor.authorMasague, Marta
dc.contributor.authorAbete, Itziar
dc.contributor.authorMoreno-Rodriguez, Anai
dc.contributor.authorCandela-Garcia, Inma
dc.contributor.authorKonieczna, Jadwiga
dc.contributor.authorGarcia-Rios, Antonio
dc.contributor.authorJuarez, Oscar Lecea
dc.contributor.authorMartin, Paco
dc.contributor.authorGoday, Albert
dc.contributor.authorZulet, M Angeles
dc.contributor.authorVaquero-Luna, Jessica
dc.contributor.authorOrea, Maria Del Carmen Sayon
dc.contributor.authorMegias, Isabel
dc.contributor.authorBaltasar, Enric
dc.contributor.authorMartinez, J Alfredo
dc.contributor.authorDaimiel, Lidia
dc.contributor.funderCIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN)
dc.contributor.funderInstituto de Salud Carlos III (ISCIII) through the Fondo de Investigación para la Salud (FIS)
dc.contributor.funderEuropean Regional Development Fund
dc.contributor.funderConsejería de Salud de la Junta de Andalucía
dc.contributor.funderEuropean Research Council
dc.date.accessioned2023-05-03T13:40:00Z
dc.date.available2023-05-03T13:40:00Z
dc.date.issued2022-04-26
dc.description.abstractTo evaluate the effect of Non-alcoholic fatty liver disease (NAFLD) status in the impact of lifestyle over Health-related quality of life (HRQoL) in patients with metabolic syndrome (MetS). Baseline and 1 year follow up data from the PREDIMED-plus cohort (men and women, 55-75 years old with overweight/obesity and MetS) were studied. Adherence to an energy-restricted Mediterranean Diet (er-MeDiet) and Physical Activity (PA) were assessed with a validated screeners. Hepatic steatosis index (HSI) was implemented to evaluate NAFLD while the SF-36 questionnaire provided HRQoL evaluation. Statistical analyses were performed to evaluate the influence of baseline NAFLD on HRQoL as affected by lifestyle during 1 year of follow up. Data from 5205 patients with mean age of 65 years and a 48% of female participants. Adjusted linear multivariate mixed regression models showed that patients with lower probability of NAFLD (HSI The evaluation of NAFLD by the HSI index in patients with MetS might identify subjects with different prospective sensitivity to lifestyle changes in terms of physical HRQoL
dc.description.versionSi
dc.identifier.citationMartínez-Urbistondo D, San Cristóbal R, Villares P, Martínez-González MÁ, Babio N, Corella D, et al. Role of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort. Front Endocrinol (Lausanne). 2022 Jun 29;13:868795
dc.identifier.doi10.3389/fendo.2022.868795
dc.identifier.issn1664-2392
dc.identifier.pmcPMC9276971
dc.identifier.pmid35846291
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276971/pdf
dc.identifier.unpaywallURLhttps://www.frontiersin.org/articles/10.3389/fendo.2022.868795/pdf
dc.identifier.urihttp://hdl.handle.net/10668/20564
dc.journal.titleFrontiers in endocrinology
dc.journal.titleabbreviationFront Endocrinol (Lausanne)
dc.language.isoen
dc.organizationHospital Universitario Reina Sofía
dc.organizationInstituto Maimónides de Investigación Biomédica de Córdoba-IMIBIC
dc.organizationHospital Universitario Virgen de la Victoria
dc.organizationInstituto de Investigación Biomédica de Málaga-IBIMA
dc.organizationSevilla
dc.page.number11
dc.publisherFrontiers Research Foundation
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.relation.projectID#340918
dc.relation.projectIDPI0458/2013
dc.relation.projectIDPS0358/2016
dc.relation.projectIDPI13/00673
dc.relation.projectIDPI13/00492
dc.relation.publisherversionhttps://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2022.868795/full
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectHRQoL
dc.subjectNAFLD
dc.subjectMediterranean diet
dc.subjectMetabolic syndrome
dc.subjectPhysical activity
dc.subject.decsCalidad de vida
dc.subject.decsEnfermedad del hígado graso no alcohólico
dc.subject.decsEstilo de vida
dc.subject.decsEstudios prospectivos
dc.subject.decsSíndrome metabólico
dc.subject.meshAged
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshLife style
dc.subject.meshMale
dc.subject.meshMetabolic syndrome
dc.subject.meshMiddle aged
dc.subject.meshNon-alcoholic fatty liver disease
dc.subject.meshProspective studies
dc.subject.meshQuality of life
dc.titleRole of NAFLD on the Health Related QoL Response to Lifestyle in Patients With Metabolic Syndrome: The PREDIMED Plus Cohort.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number13
dspace.entity.typePublication

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