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Synthetic biology approaches to actinomycete strain improvement.

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dc.contributor.authorBreitling, Rainer
dc.contributor.authorAvbelj, Martina
dc.contributor.authorBilyk, Oksana
dc.contributor.authorCarratore, Francesco Del
dc.contributor.authorFilisetti, Alessandro
dc.contributor.authorHanko, Erik K R
dc.contributor.authorIorio, Marianna
dc.contributor.authorRedondo, Rosario Pérez
dc.contributor.authorReyes, Fernando
dc.contributor.authorRudden, Michelle
dc.contributor.authorSeveri, Emmanuele
dc.contributor.authorSlemc, Lucija
dc.contributor.authorSchmidt, Kamila
dc.contributor.authorWhittall, Dominic R
dc.contributor.authorDonadio, Stefano
dc.contributor.authorGarcía, Antonio Rodríguez
dc.contributor.authorGenilloud, Olga
dc.contributor.authorKosec, Gregor
dc.contributor.authorDe Lucrezia, Davide
dc.contributor.authorPetković, Hrvoje
dc.contributor.authorThomas, Gavin
dc.contributor.authorTakano, Eriko
dc.date.accessioned2023-02-09T11:39:05Z
dc.date.available2023-02-09T11:39:05Z
dc.date.issued2021
dc.description.abstractTheir biochemical versatility and biotechnological importance make actinomycete bacteria attractive targets for ambitious genetic engineering using the toolkit of synthetic biology. But their complex biology also poses unique challenges. This mini review discusses some of the recent advances in synthetic biology approaches from an actinomycete perspective and presents examples of their application to the rational improvement of industrially relevant strains.
dc.identifier.doi10.1093/femsle/fnab060
dc.identifier.essn1574-6968
dc.identifier.pmcPMC8195692
dc.identifier.pmid34057181
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195692/pdf
dc.identifier.unpaywallURLhttps://academic.oup.com/femsle/article-pdf/368/10/fnab060/38609453/fnab060.pdf
dc.identifier.urihttp://hdl.handle.net/10668/17855
dc.issue.number10
dc.journal.titleFEMS microbiology letters
dc.journal.titleabbreviationFEMS Microbiol Lett
dc.language.isoen
dc.organizationFundación MEDINA (Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía)
dc.organizationFundación MEDINA
dc.pubmedtypeJournal Article
dc.pubmedtypeResearch Support, Non-U.S. Gov't
dc.pubmedtypeReview
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectactinobacteria
dc.subjectactinomycete
dc.subjectbiosynthesis
dc.subjectbiotechnology
dc.subjectsynthetic biology
dc.subject.meshActinobacteria
dc.subject.meshIndustrial Microbiology
dc.subject.meshMetabolic Engineering
dc.subject.meshSynthetic Biology
dc.titleSynthetic biology approaches to actinomycete strain improvement.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number368
dspace.entity.typePublication

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