Publication: Función renal, estado de volemia y furosemida en diálisis peritoneal
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Identifiers
Date
2013-10
Authors
Cirera Segura, Francisco
Martín Espejo, Jesús Lucas
Gómez Castilla, Antonia Concepción
Ojeda Guerrero, María Ángeles
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Sociedad Española de Enfermería Nefrológica
Abstract
El objetivo principal fue comparar la diuresis y la función renal de los pacientes incidentes en diálisis peritoneal y su evolución en función al uso de furosemida. El objetivo secundario fue valorar si la furosemida puede mejorar el estado de volumen. Material y métodos: Se realizó un estudio retrospectivo, comparativo, longitudinal y multicéntrico. La muestra fueron 40 pacientes. En una unidad se utilizaron diuréticos (grupo furosemida) y en otra no (grupo control). Se recogieron variables del estudio al inicio, 6 y 12 meses. El análisis se realizó con el SPSS 19. Resultados: El 57,5% de los pacientes eran hombres. La edad media fue 56,45 + 16,2 años. La etiología más prevalente fue la nefritis intersticial. Ningún paciente presentó efectos secundarios. La diuresis evolucionó igual en ambos grupos, siendo superiores en el grupo furosemida sin significación. No hallamos diferencias significativas a lo largo del estudio para la diuresis, filtrado glomerular, peso, índice masa corporal y ultrafiltración media. El 40% de los pacientes del grupo control presentaron edemas a los 6 meses frente al 17,6% del grupo furosemida. El grupo control utilizó mayor número de intercambios hipertónicos durante el primer año. El grupo furosemida mostró presiones arteriales sistólicas y diastólicas superiores y utilizó más hipotensores aunque sin significación. Conclusiones: La administración de dosis bajas de diuréticos no ha mostrado diferencias significativas para la diuresis y la función renal durante el primer año en diálisis peritoneal. Quizás por las bajas dosis, el uso de diuréticos no mejoró los parámetros relacionados con el estado de volumen.
The main object was to compare diuresis and renal function in peritoneal dialysis incident patients and their evolution according to the use of furosemide. The secondary object was to evaluate whether furosemide can improve the volume status. Material and methods: A multicentre, longitudinal, comparative, retrospective study was carried out. The sample was 40 patients.In one unit diuretics (furosemide group) were used and in another they were not (control group). Study variables were noted at the start, and after 6 and 12 months.The analysis was carried out using SPSS 19. Results: 57.5% of the patients were men. The average age was 56.45 + 16.2 yeas. The most prevalent aetiology was interstitial nephritis. No patients presented side effects.The evolution of diuresis was the same in both groups, and was higher in the furosemide group without significance. We did not find significant differences throughout the study for diuresis, glomerular filtration, weight, body mass index and mean ultrafiltration. 40% of the patients in the control group presented oedemas after 6 months compared to 17.6% in the furosemide group. The control group used a larger number of hypertonic exchanges during the first year.The furosemide group showed higher systolic and diastolic blood pressure and used more hypotensors, although without significance. Conclusions: The administration of low doses of diuretics has not shown significant differences for diuresis and renal functions during the first year on peritoneal dialysis. Perhaps on account of the low doses, the use of diuretics did not improve the parameters related to the volume status.
The main object was to compare diuresis and renal function in peritoneal dialysis incident patients and their evolution according to the use of furosemide. The secondary object was to evaluate whether furosemide can improve the volume status. Material and methods: A multicentre, longitudinal, comparative, retrospective study was carried out. The sample was 40 patients.In one unit diuretics (furosemide group) were used and in another they were not (control group). Study variables were noted at the start, and after 6 and 12 months.The analysis was carried out using SPSS 19. Results: 57.5% of the patients were men. The average age was 56.45 + 16.2 yeas. The most prevalent aetiology was interstitial nephritis. No patients presented side effects.The evolution of diuresis was the same in both groups, and was higher in the furosemide group without significance. We did not find significant differences throughout the study for diuresis, glomerular filtration, weight, body mass index and mean ultrafiltration. 40% of the patients in the control group presented oedemas after 6 months compared to 17.6% in the furosemide group. The control group used a larger number of hypertonic exchanges during the first year.The furosemide group showed higher systolic and diastolic blood pressure and used more hypotensors, although without significance. Conclusions: The administration of low doses of diuretics has not shown significant differences for diuresis and renal functions during the first year on peritoneal dialysis. Perhaps on account of the low doses, the use of diuretics did not improve the parameters related to the volume status.
Description
MeSH Terms
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Vital Signs::Blood Pressure
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Control Groups
Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Urinary Tract Physiological Phenomena::Urinary Tract Physiological Processes::Diuresis
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Natriuretic Agents::Diuretics
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Edema
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Sulfonamides::Sulfanilamides::Furosemide
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Nephritis::Nephritis, Interstitial
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Renal Replacement Therapy::Renal Dialysis::Peritoneal Dialysis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Extracorporeal Circulation::Ultrafiltration
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Body Constitution::Body Weights and Measures::Body Mass Index
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Body Weight
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Control Groups
Medical Subject Headings::Phenomena and Processes::Reproductive and Urinary Physiological Phenomena::Urinary Tract Physiological Phenomena::Urinary Tract Physiological Processes::Diuresis
Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Natriuretic Agents::Diuretics
Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Edema
Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Sulfonamides::Sulfanilamides::Furosemide
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Check Tags::Male
Medical Subject Headings::Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Nephritis::Nephritis, Interstitial
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Renal Replacement Therapy::Renal Dialysis::Peritoneal Dialysis
Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Extracorporeal Circulation::Ultrafiltration
DeCS Terms
CIE Terms
Keywords
Peritoneal dialysis, Diuretics, Residual renal funcion, Diálisis peritoneal, Diuréticos, Función renal residual
Citation
Cirera Segura F, Martín Espejo JL, Gómez Castilla AC, Ojeda Guerrero MA. Función renal, estado de volemia y furosemida en diálisis peritoneal. Enferm Nefrol. 2013; 16 (4): 271-277