Publication: Effect of Different Insulin Therapies on Obstetric-Fetal Outcomes.
dc.contributor.author | López-Tinoco, Cristina | |
dc.contributor.author | Jiménez-Blázquez, José Luis | |
dc.contributor.author | Larrán-Escandón, Laura | |
dc.contributor.author | Roca-Rodríguez, María Del Mar | |
dc.contributor.author | Bugatto, Fernando | |
dc.contributor.author | Aguilar-Diosdado, Manuel | |
dc.date.accessioned | 2023-02-08T14:37:53Z | |
dc.date.available | 2023-02-08T14:37:53Z | |
dc.date.issued | 2019-11-27 | |
dc.description.abstract | To evaluate the effectiveness of the different insulin therapies on obstetrics-fetal outcomes in women with pregestational diabetes mellitus. We enrolled 147 pregnant women with pre-existing type 1 or 2 diabetes mellitus. Clinical and biochemical parameters were analysed in relation to obstetric and fetal outcomes. 14.2% received treatment with Neutral Protamine Hagedorn insulin and short-acting insulin analogues; 19% with premixed human insulin; 40.1% with insulin glargine and lispro, 6.2% with detemir and aspart and 20% with continuous subcutaneous insulin infusion. All 5 types of treatment achieved a reduction of the mean HbA1c during pregnancy (p = 0.01). Pre-pregnancy care was carried out for 48% of patients. We found no statistically significant differences between the different insulin therapies and the obstetric-fetal outcomes. In conclusión, the different insulin therapies used in patients with pregestational diabetes mellitus does not seem to affect obstetric-fetal outcomes. | |
dc.identifier.doi | 10.1038/s41598-019-54164-4 | |
dc.identifier.essn | 2045-2322 | |
dc.identifier.pmc | PMC6881342 | |
dc.identifier.pmid | 31776421 | |
dc.identifier.pubmedURL | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881342/pdf | |
dc.identifier.unpaywallURL | https://www.nature.com/articles/s41598-019-54164-4.pdf | |
dc.identifier.uri | http://hdl.handle.net/10668/14757 | |
dc.issue.number | 1 | |
dc.journal.title | Scientific reports | |
dc.journal.titleabbreviation | Sci Rep | |
dc.language.iso | en | |
dc.organization | Hospital Universitario Puerta del Mar | |
dc.organization | Hospital Universitario Puerta del Mar | |
dc.page.number | 17650 | |
dc.pubmedtype | Journal Article | |
dc.rights | Attribution 4.0 International | |
dc.rights.accessRights | open access | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.subject.mesh | Adult | |
dc.subject.mesh | Diabetes Mellitus | |
dc.subject.mesh | Diabetes Mellitus, Type 1 | |
dc.subject.mesh | Diabetes Mellitus, Type 2 | |
dc.subject.mesh | Diabetes, Gestational | |
dc.subject.mesh | Drug Combinations | |
dc.subject.mesh | Female | |
dc.subject.mesh | Glycated Hemoglobin | |
dc.subject.mesh | Humans | |
dc.subject.mesh | Insulin | |
dc.subject.mesh | Insulin Detemir | |
dc.subject.mesh | Insulin Glargine | |
dc.subject.mesh | Insulin Lispro | |
dc.subject.mesh | Insulin, Long-Acting | |
dc.subject.mesh | Pregnancy | |
dc.subject.mesh | Pregnancy Outcome | |
dc.title | Effect of Different Insulin Therapies on Obstetric-Fetal Outcomes. | |
dc.type | research article | |
dc.type.hasVersion | VoR | |
dc.volume.number | 9 | |
dspace.entity.type | Publication |
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