Publication: Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child.
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Identifiers
Date
2022-07-09
Authors
Ibarra-Rodriguez, Maria Rosa
Garrido-Perez, Jose Ignacio
Vazquez-Rueda, Fernando
Murcia-Pascual, Francisco Javier
Wiesner-Torres, Sandra Rocio
Paredes-Esteban, Rosa Maria
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
Wolters Kluwer
Abstract
The objective of this study is to compare the outcome of treatment with drainage and urokinase (UK) versus thoracoscopy (TS) in pleural empyema secondary to complicated pneumonia. This was a retrospective study of patients with complicated parapneumonic effusions between 2008 and 2019 treated with UK or TS. Epidemiological and evolutionary data compared days of fever, antibiotic, pre- and postprocedure stay, time to radiological resolution, and complications. The results were expressed as medians and the comparisons were made by the Mann-Whitney U-test. Of 143 patients with NC, 46 were empyemas (26 men), 25 were treated with TS, and 10 were treated with UK. The remaining 11 received combined treatment, being excluded from the study. There were no significant differences between TS versus UK in age (median 4 vs. 3 years), days of fever before the procedure (4 vs. 2) and after (2 vs. 2), days of antibiotic treatment before the procedure (4 vs. 4), overall hospital stay (15 vs. 13 days), and months until radiological normalization (2 vs. 2). The complications related to the therapy were scarce in both groups and had no impact on evolution. Patients with TS had a longer preprocedural stay (4 vs. 1; P In our experience, the results obtained with both procedures are quite similar, although patients undergoing TS had a better evolution (fewer days of antibiotic and a tendency to less hospitalization), despite having been performed a priori in more evolved patients.
Description
MeSH Terms
Urokinase-Type Plasminogen Activator
Anti-Bacterial Agents
Empyema, Pleural
Hospitalization
Drainage
Anti-Bacterial Agents
Empyema, Pleural
Hospitalization
Drainage
DeCS Terms
Empiema pleural
Uroquinasa intracavitaria
Toracoscopia
Drenaje pleural
Estancia hospitalaria
Uroquinasa intracavitaria
Toracoscopia
Drenaje pleural
Estancia hospitalaria
CIE Terms
Keywords
Empyema, Fibrinolytics therapy, Thoracoscopy, Urokinase
Citation
Ibarra Rodríguez MR, Garrido Pérez JI, Rueda FV, Murcia Pascual FJ, Wiesner Torres SR, Paredes Esteban RM. Fibrinolysis versus thoracoscopy: Comparison of results in empyema management in the child. Ann Thorac Med. 2022 Jul-Sep;17(3):145-150