Publication:
Protective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus.

Simple item page
dc.contributor.authorde la Visitacion, Nestor
dc.contributor.authorRobles-Vera, Iñaki
dc.contributor.authorToral, Marta
dc.contributor.authorDuarte, Juan
dc.contributor.funderComisión Interministerial de Ciencia y Tecnología, Ministerio de Economía y competitividad (MINECO)
dc.contributor.funderJunta de Andalucía
dc.contributor.funderEuropean Union, and by the Ministerio de Economia y Competitividad, Instituto de Salud Carlos III (CIBER-CV)
dc.date.accessioned2023-02-08T14:37:11Z
dc.date.available2023-02-08T14:37:11Z
dc.date.issued2019-10-28
dc.description.abstractThe prevalence of renal and cardiovascular disease (CVD) in patients with systemic lupus erythematosus (SLE) is higher than in general populations. Recently, a causal role of gut microbiota on the development of immune responses in SLE has been described. Probiotic consumption changes the composition of gut microbiota, preventing SLE progression. The aim of this review is to explore the role of the gut microbiota in the development of renal and cardiovascular disease in SLE and how probiotics could be a therapeutic option. Despite strong evidence on the beneficial effects of probiotics in the development of autoimmunity and nephritis in SLE, only a few studies described the protective effects of Lactobacillus in important risk factors for CVD, such as endothelial dysfunction and hypertension in mice. The preventive effects of probiotics in renal and CVD in humans have not been established yet.
dc.description.sponsorshipThis work was supported by grants from Comisión Interministerial de Ciencia y Tecnología, Ministerio de Economía y competitividad (MINECO) (SAF2014-55523-R, SAF2017-84894-R) and Junta de Andalucía (Proyecto de excelencia P12-CTS-2722, and CTS 164), with funds from the European Union, and by the Ministerio de Economia y Competitividad, Instituto de Salud Carlos III (CIBER-CV). I.R.-V. is a predoctoral fellow of MINECO; N.d.l.V. is a predoctoral fellow of Junta de Andalucía and Fondo Social Europeo “FEDER una manera de hacer Europa”, and M.T. is a postdoctoral fellow of Instituto de Salud Carlos III (Sara Borrell Program).
dc.description.versionSi
dc.identifier.citationde la Visitación N, Robles-Vera I, Toral M, Duarte J. Protective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus. Nutrients. 2019 Nov 5;11(11):2676.
dc.identifier.doi10.3390/nu11112676
dc.identifier.essn2072-6643
dc.identifier.pmcPMC6893408
dc.identifier.pmid31694260
dc.identifier.pubmedURLhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893408/pdf
dc.identifier.unpaywallURLhttps://www.mdpi.com/2072-6643/11/11/2676/pdf?version=1572949610
dc.identifier.urihttp://hdl.handle.net/10668/14643
dc.issue.number11
dc.journal.titleNutrients
dc.journal.titleabbreviationNutrients
dc.language.isoen
dc.organizationInstituto de Investigación Biosanitaria ibs. GRANADA
dc.page.number15
dc.publisherMDPI AG
dc.pubmedtypeJournal Article
dc.pubmedtypeReview
dc.relation.projectIDSAF2014-55523-R
dc.relation.projectIDSAF2017-84894-R
dc.relation.projectIDP12-CTS-2722
dc.relation.projectIDCTS 164
dc.relation.publisherversionhttps://www.mdpi.com/resolver?pii=nu11112676
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectendothelial dysfunction
dc.subjectgut microbiota
dc.subjecthypertension
dc.subjectimmune response
dc.subjectnephritis
dc.subject.decsAnimales
dc.subject.decsEnfermedades cardiovasculares
dc.subject.decsEnfermedades renales
dc.subject.decsFactores de riesgo
dc.subject.decsLactobacillus
dc.subject.decsLupus eritematoso sistémico
dc.subject.decsMicrobioma gastrointestinal
dc.subject.decsProbióticos
dc.subject.decsRatones
dc.subject.decsSustancias protectoras
dc.subject.meshAnimals
dc.subject.meshCardiovascular Diseases
dc.subject.meshGastrointestinal Microbiome
dc.subject.meshKidney Diseases
dc.subject.meshLactobacillus
dc.subject.meshLupus Erythematosus, Systemic
dc.subject.meshMice
dc.subject.meshProbiotics
dc.subject.meshProtective Agents
dc.subject.meshRisk Factors
dc.titleProtective Effects of Probiotic Consumption in Cardiovascular Disease in Systemic Lupus Erythematosus.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number11
dspace.entity.typePublication

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
PMC6893408.pdf
Size:
1.45 MB
Format:
Adobe Portable Document Format
Download

Collections

Instituto de Investigación Biosanitaria de Granada (ibsGRANADA)

© 2023 – Repositorio Institucional de Salud de Andalucía - Fundación Pública Andaluza Progreso y Salud - Consejería de Salud y Consumo de la Junta de Andalucía