Publication:
Recent developments and highlights in drug hypersensitivity.

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2019-10-23

Authors

Mayorga, Cristobalina
Fernandez, Tahia D
Montañez, Maria Isabel
Moreno, Esther
Torres, María José

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Abstract

Drug hypersensitivity reactions (DHRs) are nowadays the third cause of allergy after rhinitis and asthma with a significant increase in prevalence in both adults and paediatric population with new drugs included as culprit. For this, DHRs represent not only a health problem but also a significant financial burden for affected individuals and health systems. Mislabelling DHRs is showing to be a relevant problem for both, false label of drug allergic and false label of nonallergic. All this reinforces the need to improve accurate diagnostic approaches that allow an appropriate management. Moreover, there is a need for training both, nonallergist stakeholders and patients to improve the reaction identification and therefore decrease the mislabelling. The use of allergy cards has shown to be relevant to avoid the induction of DHRs due to the prescription of wrong medication. Recent developments over the last 2 years and highlights about risk factors, diagnostic approaches, mechanisms involved as well as prevention actions, and management have been reviewed. In these papers, it has been outlined the need for correct diagnosis and de-labelling of patients previously false-reported as allergic, which will improve the management and treatment of patients with DHRs.

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Cost of Illness
Disease Management
Disease Susceptibility
Drug Hypersensitivity
Drug Labeling
Humans
Incidence
Risk Assessment
Risk Factors

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Keywords

allergy diagnosis, allergy treatment, basic mechanisms, drug allergy, epidemiology

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