Publication:
Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up.

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2022-04-08

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Torres-Collado, Laura
Garcia-de la Hera, Manuela
Cano-Ibañez, Naomi
Bueno-Cavanillas, Aurora
Vioque, Jesus

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MDPI AG
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Abstract

We evaluated the relationship between the dietary diversity score (DDS) and all-cause, CVD and cancer mortality in an adult Mediterranean population. We analyzed the data of 1540 participants from the Valencia Nutrition Survey. The DDS was estimated using a validated food frequency questionnaire and was categorized into quartiles (Q), where the first quartile indicates the lowest dietary diversity. Deaths were ascertained during an 18-year follow-up period. Cox regression models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI). There were 403 deaths during the follow-up period (40% due to CVD). An inverse association was observed between the DDS and all-cause and CVD mortality. Compared with participants in the lowest DDS quartile (Q1), participants in the highest DDS quartile (Q4) showed 32% and 45% less risk of death for all-cause and CVD mortality, in sex- and age-adjusted models, respectively. Regarding the food groups in the DDS, an inverse association was identified between total vegetable consumption diversity and all-cause and CVD mortality in the highest quartiles, (Q3 vs. Q1, HR: 0.70; 95% CI: 0.50, 0.99) and (Q4 vs. Q1, HR: 0.52; 95% CI: 0.30, 0.91), respectively. This study suggests that a higher diversity in food intake, particularly in vegetables, may be associated with a lower risk of all-cause and CVD mortality. This association should be further investigated in other wider populations.

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Adult
Cardiovascular Diseases
Diet
Follow-Up Studies
Humans
Nutrition Surveys
Proportional Hazards Models
Risk Factors
Vegetables

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Verduras
Modelos de riesgos proporcionales
Humanos
Factores de riesgo
Estudios de seguimiento
Enfermedades cardiovasculares
Encuestas nutricionales
Dieta
Adulto

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Keywords

cancer, cardiovascular disease, dietary diversity score, mortality

Citation

Torres-Collado L, García-de la Hera M, Cano-Ibañez N, Bueno-Cavanillas A, Vioque J. Association between Dietary Diversity and All-Cause Mortality: A Multivariable Model in a Mediterranean Population with 18 Years of Follow-Up. Nutrients. 2022 Apr 11;14(8):1583.