Publication:
The TREX1 Dinosaur Bites the Brain through the LINE.

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dc.contributor.authorGarcía Pérez, José Luis
dc.contributor.authorAlarcón-Riquelme, Marta E
dc.date.accessioned2023-01-25T09:51:51Z
dc.date.available2023-01-25T09:51:51Z
dc.date.issued2017
dc.description.abstractIn this issue of Cell Stem Cell, Thomas et al. (2017) define the nature of accumulated ssDNA present in the neuron and astrocyte cytoplasm of TREX1 mutated stem cell-derived organoids. Accumulated ssDNAs are derived from LINE-1 endogenous retroelements, providing new clues as to the development of Aicardi-Goutières syndrome in the neural system.
dc.identifier.doi10.1016/j.stem.2017.08.010
dc.identifier.essn1875-9777
dc.identifier.pmid28886359
dc.identifier.unpaywallURLhttp://www.cell.com/article/S1934590917303284/pdf
dc.identifier.urihttp://hdl.handle.net/10668/11566
dc.issue.number3
dc.journal.titleCell stem cell
dc.journal.titleabbreviationCell Stem Cell
dc.language.isoen
dc.organizationCentro Pfizer-Universidad de Granada-Junta de Andalucía de Genómica e Investigación Oncológica-GENYO
dc.page.number287-288
dc.pubmedtypeJournal Article
dc.pubmedtypeComment
dc.rights.accessRightsopen access
dc.subject.meshAnimals
dc.subject.meshAutoimmune Diseases
dc.subject.meshAutoimmune Diseases of the Nervous System
dc.subject.meshBrain
dc.subject.meshDinosaurs
dc.subject.meshHumans
dc.subject.meshPhosphoproteins
dc.subject.meshStem Cells
dc.titleThe TREX1 Dinosaur Bites the Brain through the LINE.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number21
dspace.entity.typePublication

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