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Clinical features and short-term outcomes of cancer patients with suspected and unsuspected pulmonary embolism: the EPIPHANY study

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dc.contributor.authorFont, Carme
dc.contributor.authorCarmona-Bayonas, Alberto
dc.contributor.authorBeato, Carmen
dc.contributor.authorReig, Oscar
dc.contributor.authorSaez, Antonia
dc.contributor.authorJimenez-Fonseca, Paula
dc.contributor.authorPlasencia, Juana M.
dc.contributor.authorCalvo-Temprano, David
dc.contributor.authorSanchez, Marcelo
dc.contributor.authorBenegas, Mariana
dc.contributor.authorBiosca, Mercedes
dc.contributor.authorVarona, Diego
dc.contributor.authorAngeles-Vicente, Maria
dc.contributor.authorFaez, Laura
dc.contributor.authordel-Pilar-Solis, Maria
dc.contributor.authorde-la-Haba, Irma
dc.contributor.authorAntonio, Maite
dc.contributor.authorMadridano, Olga
dc.contributor.authorCastanon, Eduardo
dc.contributor.authorMartinez, Maria Jose
dc.contributor.authorMarchena, Pablo
dc.contributor.authorRamchandani, Avinash
dc.contributor.authorDominguez, Angel
dc.contributor.authorPuerta, Alejandro
dc.contributor.authorMartinez-de-la-Haza, David
dc.contributor.authorPueyo, Jesus
dc.contributor.authorHernandez, Susana
dc.contributor.authorFernandez-Plaza, Angela
dc.contributor.authorMartinez-Encarnacion, Lourdes
dc.contributor.authorMartin, Mar
dc.contributor.authorMarin, Gema
dc.contributor.authorAyala, Francisco
dc.contributor.authorVicente, Vicente
dc.contributor.authorOtero, Remedios
dc.contributor.authoraffiliation[Font, Carme] Hosp Clin Barcelona, Dept Med Oncol, IDIBAPS Translat Genom & Targeted Therapeut Solid, Villarroel 170, E-08036 Barcelona, Spain
dc.contributor.authoraffiliation[Reig, Oscar] Hosp Clin Barcelona, Dept Med Oncol, IDIBAPS Translat Genom & Targeted Therapeut Solid, Villarroel 170, E-08036 Barcelona, Spain
dc.contributor.authoraffiliation[Carmona-Bayonas, Alberto] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain
dc.contributor.authoraffiliation[Angeles Vicente, Maria] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain
dc.contributor.authoraffiliation[Ayala, Francisco] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain
dc.contributor.authoraffiliation[Vicente, Vicente] Hosp Univ Morales Meseguer, Med Oncol & Hematol Dept, Murcia, Spain
dc.contributor.authoraffiliation[Beato, Carmen] Hosp Nisa Aljarafe, Dept Med Oncol, Seville, Spain
dc.contributor.authoraffiliation[Saez, Antonia] Axioma Comunicac, Dept Stat, Seville, Spain
dc.contributor.authoraffiliation[Jimenez-Fonseca, Paula] Hosp Univ Cent Asturias, Dept Med Oncol, Oviedo, Spain
dc.contributor.authoraffiliation[Faez, Laura] Hosp Univ Cent Asturias, Dept Med Oncol, Oviedo, Spain
dc.contributor.authoraffiliation[del Pilar Solis, Maria] Hosp Univ Cent Asturias, Dept Med Oncol, Oviedo, Spain
dc.contributor.authoraffiliation[Plasencia, Juana M.] Hosp Univ Morales Meseguer, Dept Radiol, Murcia, Spain
dc.contributor.authoraffiliation[Calvo-Temprano, David] Hosp Univ Cent Asturias, Dept Radiol, Oviedo, Spain
dc.contributor.authoraffiliation[Sanchez, Marcelo] Hosp Clin Barcelona, Radiodiagnost Dept, Barcelona, Spain
dc.contributor.authoraffiliation[Benegas, Mariana] Hosp Clin Barcelona, Radiodiagnost Dept, Barcelona, Spain
dc.contributor.authoraffiliation[Biosca, Mercedes] Hosp Univ Vall Hebron, Dept Med Oncol, Barcelona, Spain
dc.contributor.authoraffiliation[Varona, Diego] Hosp Univ Vall Hebron, Dept Radiol, Barcelona, Spain
dc.contributor.authoraffiliation[de la Haba, Irma] Hosp Llobregat, Hosp Duran & Reynals, Inst Catalad Oncol, Dept Med Oncol, Barcelona, Spain
dc.contributor.authoraffiliation[Antonio, Maite] Hosp Llobregat, Hosp Duran & Reynals, Inst Catalad Oncol, Dept Med Oncol, Barcelona, Spain
dc.contributor.authoraffiliation[Madridano, Olga] Hosp Infanta Sof San Sebastian Ios Reves, Dept Internal Med, Madrid, Spain
dc.contributor.authoraffiliation[Martin, Mar] Hosp Infanta Sof San Sebastian Ios Reves, Dept Internal Med, Madrid, Spain
dc.contributor.authoraffiliation[Castanon, Eduardo] Univ Navarra Clin, Dept Med Oncol, Pamplona, Spain
dc.contributor.authoraffiliation[Jose Martinez, Maria] Hosp Santa Lucia, Dept Med Oncol, Murcia, Spain
dc.contributor.authoraffiliation[Marchena, Pablo] Hosp San Juan Dios, Dept Internal Med, Esplugues Llobregat, Barcelona, Spain
dc.contributor.authoraffiliation[Ramchandani, Avinash] Hosp Insular Gran Canaria, Dept Med Oncol, Las Palmas Gran Canaria, Spain
dc.contributor.authoraffiliation[Dominguez, Angel] Hosp Nisa Aljarafe, Dept Radiol, Seville, Spain
dc.contributor.authoraffiliation[Puerta, Alejandro] Hosp Reina Sofia, Dept Radiol, Murcia, Spain
dc.contributor.authoraffiliation[Martinez de la Haza, David] Hosp Llobregat, Hosp Duran & Reynals, Inst Catalad Oncol, Dept Radiol, Barcelona, Spain
dc.contributor.authoraffiliation[Pueyo, Jesus] Univ Navarra Clin, Dept Radiol, Pamplona, Spain
dc.contributor.authoraffiliation[Hernandez, Susana] Hosp Infanta Sofia San Sebastian los Reves, Dept Radiol, Madrid, Spain
dc.contributor.authoraffiliation[Fernandez-Plaza, Angela] Hosp Santa Lucia, Dept Radiol, Murcia, Spain
dc.contributor.authoraffiliation[Martinez-Encarnacion, Lourdes] Hosp Santa Lucia, Dept Radiol, Murcia, Spain
dc.contributor.authoraffiliation[Marin, Gema] Hosp Clin Univ Virgen la Arrixaca, Dept Med Oncol, Murcia, Spain
dc.contributor.authoraffiliation[Otero, Remedios] HUVR IBiS, CIBERES, Dept Pneumol, Seville, Spain
dc.contributor.funderLEO Pharma Spain
dc.contributor.groupAsociación para la Investigación de la Enfermedad Tromboembólica de la región de Murcia
dc.date.accessioned2023-02-12T02:22:06Z
dc.date.available2023-02-12T02:22:06Z
dc.date.issued2017-01-04
dc.description.abstractThe study aimed to identify predictors of overall 30-day mortality in cancer patients with pulmonary embolism including suspected pulmonary embolism (SPE) and unsuspected pulmonary embolism (UPE) events. Secondary outcomes included 30-and 90-day major bleeding and venous thromboembolism (VTE) recurrence.The study cohort included 1033 consecutive patients with pulmonary embolism from the multicentre observational ambispective EPIPHANY study (March 2006-October 2014). A subgroup of 497 patients prospectively assessed for the study were subclassified into three work-up scenarios (SPE, truly asymptomatic UPE and UPE with symptoms) to assess outcomes.The overall 30-day mortality rate was 14%. The following variables were associated with the overall 30day mortality on multivariate analysis: VTE history, upper gastrointestinal cancers, metastatic disease, cancer progression, performance status, arterial hypotension 110 beats.min(-1), basal oxygen saturation
dc.description.versionSi
dc.identifier.citationFont C, Carmona-Bayonas A, Beato C, Reig Ò, Sáez A, Jiménez-Fonseca P, et al. Clinical features and short-term outcomes of cancer patients with suspected and unsuspected pulmonary embolism: the EPIPHANY study. Eur Respir J. 2017 Jan 4;49(1):1600282.
dc.identifier.doi10.1183/13993003.00282-2016
dc.identifier.essn1399-3003
dc.identifier.issn0903-1936
dc.identifier.unpaywallURLhttps://erj.ersjournals.com/content/erj/49/1/1600282.full.pdf
dc.identifier.urihttp://hdl.handle.net/10668/19113
dc.identifier.wosID397423500007
dc.issue.number1
dc.journal.titleEuropean respiratory journal
dc.journal.titleabbreviationEur. resp. j.
dc.language.isoen
dc.organizationInstituto de Biomedicina de Sevilla-IBIS
dc.organizationHospital Universitario Virgen del Rocío
dc.page.number12
dc.provenanceRealizada la curación de contenido 02/04/2025
dc.publisherEuropean respiratory soc journals ltd
dc.relation.publisherversionhttps://publications.ersnet.org/lookup/pmid/28052954
dc.rights.accessRightsRestricted Access
dc.subjectAdversely impact survival
dc.subjectVenous thromboembolism
dc.subjectOutpatient management
dc.subjectPrognostic model
dc.subjectSeverity index
dc.subjectRisk
dc.subjectGuidelines
dc.subjectDiagnosis
dc.subject.decsEmbolia pulmonar
dc.subject.decsNeoplasias
dc.subject.decsPacientes
dc.subject.decsMortalidad
dc.subject.decsTrabajo
dc.subject.decsSaturación de oxígeno
dc.subject.decsTromboembolia venosa
dc.subject.decsNeoplasias gastrointestinales
dc.subject.meshMultivariate Analysis
dc.subject.meshHemorrhage
dc.subject.meshGastrointestinal Neoplasms
dc.subject.meshPulmonary Embolism
dc.subject.meshNeoplasms, Second Primary
dc.subject.meshNeoplastic Processes
dc.subject.meshOxygen Saturation
dc.subject.meshVenous Thromboembolism
dc.titleClinical features and short-term outcomes of cancer patients with suspected and unsuspected pulmonary embolism: the EPIPHANY study
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number49
dc.wostypeArticle
dspace.entity.typePublication

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