Publication: Total and cardiovascular mortality risk according to KDIGO guidelines classification in type 2 diabetic patients.
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Date
2019-03-15
Authors
Medrano Navarro, Ana Lidia
Justel Enríquez, Alicia
Alameda Serrano, Javier
Blasco Lamarca, Yolanda
Sáenz Abad, Daniel
Gimeno Orna, José Antonio
Advisors
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Abstract
Our aim was to assess the usefulness of KDIGO 2012 risk classification to predict total and cardiovascular mortality in type 2 diabetes mellitus (DM2). Prospective cohort study that included DM2 patients. Clinical end-points were total and cardiovascular mortality. The main predictive variable was KDIGO risk classification, which is a combination of urinary albumin excretion and glomerular filtration rate. The predictive value was evaluated by the integrated discrimination improvement (IDI) index. 453 patients (39.3% males, aged 64.9 [SD 9.3] and with a mean diabetes duration of 10.4 [SD 7.5] years) were included. During a median follow-up of 13 years, mortality rates per 1000 patients/year (26.5 vs. 45.1 vs. 79,2 vs. 109,8; p KDIGO risk classification can effectively stratify total and cardiovascular mortality risk in DM2 patients.
Description
MeSH Terms
Adult
Albuminuria
Analysis of Variance
Cardiovascular Diseases
Cause of Death
Chi-Square Distribution
Creatine
Diabetes Mellitus, Type 2
Female
Glomerular Filtration Rate
Guidelines as Topic
Humans
Male
Middle Aged
Prospective Studies
Renal Insufficiency, Chronic
Reproducibility of Results
Risk Assessment
Sex Factors
Statistics, Nonparametric
Stroke
Albuminuria
Analysis of Variance
Cardiovascular Diseases
Cause of Death
Chi-Square Distribution
Creatine
Diabetes Mellitus, Type 2
Female
Glomerular Filtration Rate
Guidelines as Topic
Humans
Male
Middle Aged
Prospective Studies
Renal Insufficiency, Chronic
Reproducibility of Results
Risk Assessment
Sex Factors
Statistics, Nonparametric
Stroke
DeCS Terms
CIE Terms
Keywords
Diabetes mellitus, Prognosis, Pronóstico, Supervivencia, Survival