Publication: The marine biodiscovery pipeline and ocean medicines of tomorrow
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2016-02-01
Authors
Jaspars, Marcel
De Pascale, Donatella
Andersen, Jeanette H.
Reyes, Fernando
Crawford, Alexander D.
Ianora, Adrianna
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Cambridge univ press
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Abstract
Marine organisms possess the capacity to produce a variety of unique and biologically potent natural products for treating human diseases, many of which are currently commercially available or are in advanced clinical trials. Here we provide a short review on progress in the field and discuss a case study of an EU-funded project, PharmaSea, which aims to discover novel products for the treatment of infections, inflammation and neurodegenerative diseases. Research in this sector is opening new doors for harnessing the potential of marine natural products with pharmaceutical properties.
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Keywords
drug discovery, ocean medicines, PharmaSea project, Natural-products, Pain, Systems