Publication: Activated protein C, severe sepsis and 28-day mortality.
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Identifiers
Date
2012-05-20
Authors
Torre-Prados, M de la
García-de la Torre, A
Nieto-González, M
Lucena-González, I
Escobar-Conesa, R
García-Alcántara, A
Enguix-Armada, A
Advisors
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
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Abstract
Protein C (PC) de ciency is prevalent in severe sepsis, studies showing that more than 80% of patients with severe sepsis
have a baseline PC level below the lower limit of normal [1,2]. The aim of the study was to relate the anticoagulation activity evaluated by PC, with clinical parameters and 28-day mortality.
Description
MeSH Terms
Medical Subject Headings::Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Blood Coagulation Disorders::Blood Coagulation Disorders, Inherited::Protein C Deficiency
Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Blood Physiological Phenomena::Blood Physiological Processes::Hemostasis::Blood Coagulation
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Infection::Sepsis::Shock, Septic
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzyme Precursors::Protein C
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
Medical Subject Headings::Phenomena and Processes::Circulatory and Respiratory Physiological Phenomena::Blood Physiological Phenomena::Blood Physiological Processes::Hemostasis::Blood Coagulation
Medical Subject Headings::Diseases::Bacterial Infections and Mycoses::Infection::Sepsis::Shock, Septic
Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzyme Precursors::Protein C
Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
Medical Subject Headings::Named Groups::Persons::Age Groups::Adult
DeCS Terms
CIE Terms
Keywords
Deficiencia de Proteína C, Coagulación Sanguínea, Choque Séptico, Proteina C, Humanos
Citation
Torre-Prados M de la., García-de la Torre A., Nieto-González M., Lucena-González I., Escobar-Conesa R., García-Alcántara A. et al. Activated protein C, severe sepsis and 28-day mortality. Critical Care. 2012;16(Suppl. 1):S8-S9