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Antibacterial Activity of Moroccan Zantaz Honey and the Influence of Its Physicochemical Parameters Using Chemometric Tools

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dc.contributor.authorElamine, Youssef
dc.contributor.authorImtara, Hamada
dc.contributor.authorGraca Miguel, Maria
dc.contributor.authorAnjos, Ofelia
dc.contributor.authorEstevinho, Leticia M.
dc.contributor.authorAlaiz, Manuel
dc.contributor.authorGiron-Calle, Julio
dc.contributor.authorVioque, Javier
dc.contributor.authorMartin, Jesus
dc.contributor.authorLyoussi, Badiaa
dc.contributor.authoraffiliation[Elamine, Youssef] Univ Pablo de Olavide, Inst Grasa CSIC, Edificio 46,Carretera Utrera,Km 1, Seville 41013, Spain
dc.contributor.authoraffiliation[Alaiz, Manuel] Univ Pablo de Olavide, Inst Grasa CSIC, Edificio 46,Carretera Utrera,Km 1, Seville 41013, Spain
dc.contributor.authoraffiliation[Giron-Calle, Julio] Univ Pablo de Olavide, Inst Grasa CSIC, Edificio 46,Carretera Utrera,Km 1, Seville 41013, Spain
dc.contributor.authoraffiliation[Vioque, Javier] Univ Pablo de Olavide, Inst Grasa CSIC, Edificio 46,Carretera Utrera,Km 1, Seville 41013, Spain
dc.contributor.authoraffiliation[Elamine, Youssef] Univ Sidi Mohamed Ben Abdellah, Lab Nat Subst Pharmacol Environm Modeling Hlth &, Fes 30000, Morocco
dc.contributor.authoraffiliation[Lyoussi, Badiaa] Univ Sidi Mohamed Ben Abdellah, Lab Nat Subst Pharmacol Environm Modeling Hlth &, Fes 30000, Morocco
dc.contributor.authoraffiliation[Imtara, Hamada] Arab Amer Univ Palestine, Fac Arts & Sci, POB 240, Jenin, Palestine
dc.contributor.authoraffiliation[Graca Miguel, Maria] Univ Algarve, Fac Sci & Technol, Mediterranean Inst Agr Environm & Dev, Dept Chem & Pharm, Campus Gambelas, P-8005139 Faro, Portugal
dc.contributor.authoraffiliation[Anjos, Ofelia] Inst Politecn Castelo Branco, P-6001909 Castelo Branco, Portugal
dc.contributor.authoraffiliation[Anjos, Ofelia] Univ Lisbon, Ctr Estudos Florestais, Inst Super Agron, P-1349017 Lisbon, Portugal
dc.contributor.authoraffiliation[Anjos, Ofelia] Ctr Biotecnol Plantas Beira Interior, P-6001909 Castelo Branco, Portugal
dc.contributor.authoraffiliation[Estevinho, Leticia M.] Inst Politecn Braganca, Ctr Invest Montanha CIMO, P-5300252 Braganca, Portugal
dc.contributor.authoraffiliation[Martin, Jesus] Fdn MEDINA, Avda Conocimiento 34, Granada 18016, Spain
dc.contributor.funderC.S.I.C. Program for Scientific Cooperation for Development (Program I-COOP + 2018)
dc.contributor.funderCEF-Forest Research Centre - Fundacao para a Ciencia e a Tecnologia I.P. (FCT), Portugal
dc.date.accessioned2023-02-12T02:22:47Z
dc.date.available2023-02-12T02:22:47Z
dc.date.issued2021-05-01
dc.description.abstractThe emergence of multidrug-resistant bacteria has prompted the development of alternative therapies, including the use of natural products with antibacterial properties. The antibacterial properties of Zantaz honey produced in the Moroccan Atlas Mountains against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus was evaluated and analyzed using chemometric tools. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) against S. aureus were the lowest (112.5 +/- 54.5 mg/mL), revealing that this species was most sensitive to Zantaz honey. P. aeruginosa showed an intermediate sensitivity (MIC= 118.75 +/- 51.9 mg/mL), while E. coli was the most resistant to treatment (MIC = 175 +/- 61.2 mg/mL). Content of monosaccharides, certain minerals, and phenolic compounds correlated with antibacterial activity (p
dc.identifier.doi10.3390/app11104675
dc.identifier.essn2076-3417
dc.identifier.unpaywallURLhttps://www.mdpi.com/2076-3417/11/10/4675/pdf?version=1621492376
dc.identifier.urihttp://hdl.handle.net/10668/19246
dc.identifier.wosID662631200001
dc.issue.number10
dc.journal.titleApplied sciences-basel
dc.journal.titleabbreviationAppl. sci.-basel
dc.language.isoen
dc.organizationFundación MEDINA (Centro de Excelencia en Investigación de Medicamentos Innovadores en Andalucía)
dc.organizationFundación MEDINA
dc.publisherMdpi
dc.rightsAttribution 4.0 International
dc.rights.accessRightsopen access
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectBupleurum spinosum
dc.subjectmethyl syringate
dc.subjectEscherichia coli
dc.subjectPseudomonas aeruginosa
dc.subjectStaphylococcus aureus
dc.subjectManuka honey
dc.subjectComponents
dc.titleAntibacterial Activity of Moroccan Zantaz Honey and the Influence of Its Physicochemical Parameters Using Chemometric Tools
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number11
dc.wostypeArticle
dspace.entity.typePublication

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