Publication:
Night-shift work and breast and prostate cancer risk: updating the evidence from epidemiological studies.

dc.contributor.authorSalamanca-Fernández, E
dc.contributor.authorRodríguez-Barranco, M
dc.contributor.authorGuevara, M
dc.contributor.authorArdanaz, E
dc.contributor.authorOlry de Labry Lima, A
dc.contributor.authorSánchez, M J
dc.date.accessioned2023-01-25T10:21:10Z
dc.date.available2023-01-25T10:21:10Z
dc.date.issued2018-08-29
dc.description.abstractIt has been hypothesized that circadian disruption is related to higher cancer risk. Since the International Agency for Research on Cancer classified shift work involving circadian disruption as probably carcinogenic to humans (Group 2A), multiple studies have been conducted to test this hypothesis. The aim of this systematic review was to summarize the findings and evaluate the quality of existing epidemiological studies (case-control and cohort studies) on the relationship between night-shift work and breast and prostate cancer risk. Thirty-three epidemiological studies investigating the relationship between night-shift work and breast (n = 26) or prostate (n = 8) cancer risk were included (one paper included both sites). The Newcastle-Ottawa Scale for the quality of non-randomized studies was used to assess the risk of bias of the publications. The studies included were heterogeneous regarding population (general population, nurses working in rotating shifts, and other) and measurement of exposure to night-shift work (ever vs. never exposure, short vs. long-term, rotating vs. permanent) and, thus, a diversity of outcomes were observed even within the same type of cancer. In summary, 62.5% works found some type of association between night-shift work and increased risk of cancer, for both breast and prostate. The risk of bias scored an average of 7.5 over 9 stars. Due to the limitations inherent in these studies, the evidence of a possible association between night-shift work and breast or prostate cancer risk remains uncertain and more studies providing greater control of exposure and confounding factors are required. Despite the lack of conclusive evidence, application of the precautionary principle seems advisable.
dc.identifier.doi10.23938/ASSN.0307
dc.identifier.essn2340-3527
dc.identifier.pmid30063040
dc.identifier.unpaywallURLhttps://doi.org/10.23938/assn.0307
dc.identifier.urihttp://hdl.handle.net/10668/12782
dc.issue.number2
dc.journal.titleAnales del sistema sanitario de Navarra
dc.journal.titleabbreviationAn Sist Sanit Navar
dc.language.isoen
dc.organizationEscuela Andaluza de Salud Pública-EASP
dc.organizationHospital Universitario San Cecilio
dc.page.number211-226
dc.pubmedtypeJournal Article
dc.pubmedtypeSystematic Review
dc.rights.accessRightsopen access
dc.subjectBreast cancer. Prostate cancer. Shift work. Circadian disruption. Light at night.
dc.subject.meshBreast Neoplasms
dc.subject.meshCase-Control Studies
dc.subject.meshCohort Studies
dc.subject.meshFemale
dc.subject.meshHumans
dc.subject.meshMale
dc.subject.meshProstatic Neoplasms
dc.subject.meshRisk Assessment
dc.subject.meshShift Work Schedule
dc.titleNight-shift work and breast and prostate cancer risk: updating the evidence from epidemiological studies.
dc.title.alternativeNight-shift work and breast and prostate cancer risk: updating the evidence from epidemiological studies.
dc.typeresearch article
dc.type.hasVersionVoR
dc.volume.number41
dspace.entity.typePublication
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