Publication: A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study.
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Date
2017-04-13
Authors
Risslegger, B
Zoran, T
Lackner, M
Aigner, M
Sánchez-Reus, F
Rezusta, A
Chowdhary, A
Taj-Aldeen, S J
Arendrup, M C
Oliveri, S
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Abstract
A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. A total of 370 cases from 21 countries were evaluated. The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.
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MeSH Terms
Amphotericin B
Antifungal Agents
Aspergillosis
Aspergillus
Epidemiological Monitoring
Europe
Humans
Microbial Sensitivity Tests
Prevalence
Prospective Studies
Antifungal Agents
Aspergillosis
Aspergillus
Epidemiological Monitoring
Europe
Humans
Microbial Sensitivity Tests
Prevalence
Prospective Studies
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Keywords
Amphotericin B, Aspergillosis, Aspergillus terreus, Crytic species, In vitrosusceptibility